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HNF4A

hepatocyte nuclear factor 4, alpha

Synonyms:
HNF4, HNF4a7, HNF4a8, HNF4a9, HNF4alpha, MODY, MODY1, NR2A1, NR2A21, TCF, TCF14
Species:
UniProtKB ID:
Gene ID:
  • Human(3172) Summary: The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012]
  • Mouse(15378) hepatic nuclear factor 4, alpha
  • Rat(25735) hepatocyte nuclear factor 4, alpha
  • cow(509200) hepatocyte nuclear factor 4, alpha
  • sheep(100534656) hepatocyte nuclear factor 4, alpha
  • dog(485884) hepatocyte nuclear factor 4, alpha
  • Zebrafish(322358) hepatocyte nuclear factor 4, alpha
  • chicken(419198) hepatocyte nuclear factor 4, alpha
  • domestic guinea pig(100713275) hepatocyte nuclear factor 4, alpha
  • naked mole-rat(101710133) hepatocyte nuclear factor 4, alpha
  • domestic cat(101092841) hepatocyte nuclear factor 4, alpha
  • Horse(100056007) hepatocyte nuclear factor 4, alpha

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Small Molecule - Activator

Product Number
Description
Species
Alverine citrate salt, European Pharmacopoeia (EP) Reference Standard,
Species
human
Alverine citrate, British Pharmacopoeia (BP) Reference Standard,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-HNF4A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-HNF4A antibody produced in mouse, clone 1F12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-Phospho-HNF4A-S304 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
western blot
Anti-Phospho-HNF4A-S304 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
ANTI-HNF4A antibody produced in mouse, clone 1F2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Hnf4a,
Species
mouse
MISSION® esiRNA, targeting human HNF4A,
Species
human