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A0424

Alverine citrate salt

Name: Alverine citrate salt
Brand: ALDRICH

Synonym(s):

N-Ethyl-3,3′-diphenyldipropylamine, NSC 35459

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About This Item

Empirical Formula (Hill Notation):

C₂₀H₂₇N · C₆H₈O₇

CAS Number:

5560-59-8

Molecular Weight:

473.56

NACRES:

NA.22

PubChem Substance ID:

57653816

UNSPSC Code:

12352100

EC Number:

226-929-3

MDL number:

MFCD00035086

Form:

powder

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Properties

form

powder

Quality Level

200

SMILES string

OC(=O)CC(O)(CC(O)=O)C(O)=O.CCN(CCCc1ccccc1)CCCc2ccccc2

InChI

1S/C20H27N.C6H8O7/c1-2-21(17-9-15-19-11-5-3-6-12-19)18-10-16-20-13-7-4-8-14-20;7-3(8)1-6(13,5(11)12)2-4(9)10/h3-8,11-14H,2,9-10,15-18H2,1H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChI key

RYHCACJBKCOBTJ-UHFFFAOYSA-N

Gene Information

human ... HNF4A(3172), HTR1A(3350)

Description

Application

Used for studies of pharmacological activity including:

Synergism with fluconazole against Saccharomyces cerevisiae and Candida albicans
Efficacy of combination with simeticone on abdominal pain associated with irritable bowel syndrome
Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis
Drug effects viewed from a signal transduction network perspective
Enhanced cytotoxic effect of proteasome inhibitor MG132
Mechanism of action on phasic smooth muscles

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number

018F0643V

018F0643

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A rapid and most sensitive liquid chromatography/tandem mass spectrometry method for simultaneous determination of alverine and its major metabolite, para hydroxy alverine, in human plasma: application to a pharmacokinetic and bioequivalence study.

Chinmoy Ghosh et al.

Drug testing and analysis, 2(6), 284-291 (2010-06-22)

A rapid and highly sensitive method for the determination of alverine (ALV) and its metabolite, para hydroxy alverine (PHA), in human plasma using LC-MS/MS in positive ion electrospray ionization (ESI) in multiple reactions monitoring (MRM) mode was developed and validated.

Alverine citrate plus simethicone reduces cecal intubation time in colonoscopy - a randomized study.

Engin Altintaş et al.

The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 19(3), 174-179 (2008-12-31)

Successful colonoscopy depends on the insertion of the instrument to the cecum, a detailed examination, and minimal discomfort to the patient during the procedure. The aim of this study was to determine the effects of alverine citrate plus simethicone on

A general practice study to compare alverine citrate with mebeverine hydrochloride in the treatment of irritable bowel syndrome.

G J Tudor

The British journal of clinical practice, 40(7), 276-278 (1986-07-01)

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Global Trade Item Number

SKU	GTIN
A0424-5G	04061832854519