CN
IL6R
interleukin 6 receptor
Synonyms:
CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80
Species:
Human IL6R (3570), Rat Il6r (24499), domestic guinea pig Il6r (100730490), domestic cat IL6R (101085689), Zebrafish il6r (100135755), dog IL6R (612271), cow IL6R (507359), sheep IL6R (101103369), naked mole-rat Il6r (101704925)
UniProtKB ID:
Gene ID:
- Human(3570) Summary: This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011]
- Rat(24499) interleukin 6 receptor
- domestic guinea pig(100730490) interleukin 6 receptor
- domestic cat(101085689) interleukin 6 receptor
- Zebrafish(100135755) interleukin 6 receptor
- dog(612271) interleukin 6 receptor
- cow(507359) interleukin 6 receptor
- sheep(101103369) interleukin 6 receptor
- naked mole-rat(101704925) interleukin 6 receptor
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CD126 Antibody, clone B-R6, clone B-R6, Chemicon®, from mouse,
Species Reactivity
human
Application
ELISA
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
Monoclonal Anti-IL6R antibody produced in mouse, clone 2G6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-IL6R antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-IL6R antibody produced in mouse, clone 1E11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Proteins
Product Number
Description
Species
sIL-6 Receptor alpha human, recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Species
human
esiRNA
Product Number
Description
Species