Merck
CN

KCNQ5

potassium voltage-gated channel, KQT-like subfamily, member 5

Synonyms:
Kv7.5
Species:
UniProtKB ID:
Gene ID:
  • Human(56479) Summary: This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
  • Mouse(226922) potassium voltage-gated channel, subfamily Q, member 5
  • Rat(259273) potassium voltage-gated channel, KQT-like subfamily, member 5
  • chicken(421866) potassium voltage-gated channel, KQT-like subfamily, member 5
  • naked mole-rat(101704304) potassium voltage-gated channel, KQT-like subfamily, member 5
  • sheep(100174987) potassium voltage-gated channel, KQT-like subfamily, member 5
  • Domestic Rabbit(100328657) potassium voltage-gated channel, KQT-like subfamily, member 5
  • domestic guinea pig(100721474) potassium voltage-gated channel, KQT-like subfamily, member 5
  • domestic cat(101092113) potassium voltage-gated channel, KQT-like subfamily, member 5
  • Horse(100071357) potassium voltage-gated channel, KQT-like subfamily, member 5
  • cow(613605) potassium voltage-gated channel, KQT-like subfamily, member 5
  • dog(474965) potassium voltage-gated channel, KQT-like subfamily, member 5

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Small Molecule - Activator

Product Number
Description
Species
BMS 204352, ≥98% (HPLC),
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-KCNQ5 antibody produced in mouse, clone 2E2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-KCNQ5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-Potassium Channel KCNQ5 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
canine, chimpanzee, feline, giant panda, human, rat, rhesus macaque
Application
immunohistochemistry
western blot

Small Molecule - Blocker

Product Number
Description
Species
Retigabine, analytical standard,
Species
human
Guanidine hydrochloride solution, Colorless liquid, 7.8 - 8.3 M, pH- 4.5 - 5.5,
Species
human
Guanidine hydrochloride solution, BioUltra, ~8 M in H2O,
Species
human
3,4-Diaminopyridine, ≥98%,
Species
human
Guanidine hydrochloride, BioUltra, for molecular biology, ≥99.5% (AT),
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
N-Ethylmaleimide, crystalline, ≥98% (HPLC),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Kcnq5,
Species
mouse
MISSION® esiRNA, targeting human KCNQ5,
Species
human