KDR
kinase insert domain receptor (a type III receptor tyrosine kinase)
Synonyms:
CD309, FLK1, VEGFR, VEGFR2
Species:
Human KDR (3791), Mouse Kdr (16542), Rat Kdr (25589), chicken KDR (395323), Zebrafish kdr (554230), Thale Cress KDR (839585), dog KDR (482154), Goat KDR (100860836), cow KDR (407170), Horse KDR (100033959) ...More
UniProtKB ID:
Gene ID:
- Human(3791) Summary: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
- Mouse(16542) kinase insert domain protein receptor
- Rat(25589) kinase insert domain receptor
- chicken(395323) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Zebrafish(554230) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Thale Cress(839585) basic helix-loop-helix protein KIDARI
- dog(482154) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Goat(100860836) kinase insert domain receptor (a type III receptor tyrosine kinase)
- cow(407170) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Horse(100033959) kinase insert domain receptor (a type III receptor tyrosine kinase)
- domestic cat(101090260) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Domestic Rabbit(100008607) kinase insert domain receptor (a type III receptor tyrosine kinase)
- sheep(443087) vascular endothelial growth factor receptor-2
- naked mole-rat(101726029) kinase insert domain receptor (a type III receptor tyrosine kinase)
- domestic guinea pig(100726761) kinase insert domain receptor (a type III receptor tyrosine kinase)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Vascular Endothelial Growth Factor Receptor-2 (KDR)−Biotin Conjugate antibody, Mouse monoclonal, clone 260.4, KDR-2, purified from hybridoma cell culture,
Species Reactivity
human
Application
western blot
Anti-phospho-VEGFR2 (pTyr1175) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-KDR (AB1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-KDR (AB2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-KDR antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, horse, human, pig
Application
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
KDR Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant, human KDR amino acids 790-end,
for use in Kinase Assays.,
for use in Kinase Assays.,
Species
human
VEGF Receptor-2 (Flk-1, KDR)/Fc Chimera human, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Species
human