MMP17
matrix metallopeptidase 17 (membrane-inserted)
Synonyms:
MT4-MMP
Species:
Human MMP17 (4326), Mouse Mmp17 (23948), Rat Mmp17 (288626), cow MMP17 (513072), sheep MMP17 (101117966), domestic guinea pig Mmp17 (100718894), naked mole-rat Mmp17 (101714022), Horse MMP17 (100062342), dog MMP17 (609890), domestic cat MMP17 (101098897)
UniProtKB ID:
Gene ID:
- Human(4326) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage. [provided by RefSeq, Jul 2008]
- Mouse(23948) matrix metallopeptidase 17
- Rat(288626) matrix metallopeptidase 17
- cow(513072) matrix metallopeptidase 17 (membrane-inserted)
- sheep(101117966) matrix metallopeptidase 17 (membrane-inserted)
- domestic guinea pig(100718894) matrix metallopeptidase 17 (membrane-inserted)
- naked mole-rat(101714022) matrix metallopeptidase 17 (membrane-inserted)
- Horse(100062342) matrix metallopeptidase 17 (membrane-inserted)
- dog(609890) matrix metallopeptidase 17 (membrane-inserted)
- domestic cat(101098897) matrix metallopeptidase 17 (membrane-inserted)
- chicken(416801) matrix metallopeptidase 17 (membrane-inserted)
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