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Merck
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PSMB10

proteasome (prosome, macropain) subunit, beta type, 10

Synonyms:
LMP10, MECL1, beta2i
Species:
UniProtKB ID:
Gene ID:
  • Human(5699) Summary: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. [provided by RefSeq, Jul 2008]
  • Mouse(19171) proteasome (prosome, macropain) subunit, beta type 10
  • Rat(291983) proteasome (prosome, macropain) subunit, beta type 10
  • domestic cat(101082199) proteasome (prosome, macropain) subunit, beta type, 10
  • naked mole-rat(101701334) proteasome (prosome, macropain) subunit, beta type, 10
  • dog(489749) proteasome (prosome, macropain) subunit, beta type, 10
  • domestic guinea pig(100730197) proteasome (prosome, macropain) subunit, beta type, 10
  • Zebrafish(64280) proteasome (prosome, macropain) subunit, beta type, 10
  • sheep(101116929) proteasome (prosome, macropain) subunit, beta type, 10
  • cow(282328) proteasome (prosome, macropain) subunit, beta type, 10

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Anti PSMB10 Antibody, clone 23GB2170, Rabbit Monoclonal, clone 23GB2170, recombinant rabbit monoclonal, expressed in HEK293 cells,
Species Reactivity
human, rat
Application
flow cytometry
immunofluorescence

western blot
Anti-PSMB10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-PSMB10 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, human, mouse, pig, rat
Application
western blot
KD-Validated Anti PSMB10 Antibody, clone 23GB2165, Rabbit Monoclonal, clone 23GB2165, recombinant rabbit monoclonal, expressed in HEK293 cells,
Species Reactivity
human, rat
Application
flow cytometry
western blot
Anti-PSMB10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Psmb10,
Species
mouse