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STAT2

signal transducer and activator of transcription 2, 113kDa

Synonyms:
ISGF-3, P113, STAT113
Species:
UniProtKB ID:
Gene ID:
  • Human(6773) Summary: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
  • Mouse(20847) signal transducer and activator of transcription 2
  • Rat(288774) signal transducer and activator of transcription 2
  • dog(481111) signal transducer and activator of transcription 2, 113kDa
  • sheep(101108211) signal transducer and activator of transcription 2, 113kDa
  • cow(511023) signal transducer and activator of transcription 2, 113kDa
  • naked mole-rat(101707295) signal transducer and activator of transcription 2, 113kDa
  • domestic cat(101099224) signal transducer and activator of transcription 2, 113kDa
  • domestic guinea pig(100719719) signal transducer and activator of transcription 2, 113kDa
  • Zebrafish(565200) signal transducer and activator of transcription 2

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-STAT2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Monoclonal Anti-STAT2 antibody produced in mouse, clone 5G7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti STAT2 Antibody, clone 24GB2095, Rabbit Monoclonal, clone 24GB2095, recombinant rabbit monoclonal, expressed in HEK293 cells,
Species Reactivity
human
Application
flow cytometry
immunofluorescence

western blot
Anti-STAT2 Antibody, clone 1F7 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey, mouse
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-STAT2 antibody produced in rabbit, ,
Species Reactivity
mouse, rat
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human STAT2,
Species
human
MISSION® esiRNA, targeting mouse Stat2,
Species
mouse