CN
THRB
thyroid hormone receptor, beta
Synonyms:
C-ERBA-2, C-ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2
Species:
Human THRB (7068), Mouse Thrb (21834), Rat Thrb (24831), Domestic Rabbit THRB (100303763), chicken THRB (396431), cow THRB (788329), domestic cat THRB (101084821), Horse THRB (100051615), dog THRB (403599), naked mole-rat Thrb (101719651) ...More
UniProtKB ID:
Gene ID:
- Human(7068) Summary: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
- Mouse(21834) thyroid hormone receptor beta
- Rat(24831) thyroid hormone receptor beta
- Domestic Rabbit(100303763) thyroid hormone receptor, beta
- chicken(396431) thyroid hormone receptor, beta
- cow(788329) thyroid hormone receptor, beta
- domestic cat(101084821) thyroid hormone receptor, beta
- Horse(100051615) thyroid hormone receptor, beta
- dog(403599) thyroid hormone receptor, beta
- naked mole-rat(101719651) thyroid hormone receptor, beta
- domestic guinea pig(100721125) thyroid hormone receptor, beta
- Zebrafish(30607) thyroid hormone receptor beta
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Custom Gene Products
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Small Molecule - Agonist
Product Number
Description
Species
L-Thyroxine (T4) solution, 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
3,3′,5-Triiodo-L-thyronine (T3) solution, 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-THRB antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
ELISA
western blot
western blot
Anti-phospho-TR-β1 (pSer142) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-Thyroid Hormone Receptor β, N-Terminal antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-THRB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-Thyroid Hormone Receptor β-1 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, rat
Application
western blot
Small Molecule - Blocker
Product Number
Description
Species
Proteins
Product Number
Description
Species
esiRNA
Product Number
Description
Species