Skip to Content
Merck
CN

102407

4-Fluorophenylacetonitrile

99%

Synonym(s):

4-Fluorobenzyl cyanide

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Linear Formula:
FC6H4CH2CN
CAS Number:
459-22-3
Molecular Weight:
135.14
NACRES:
NA.22
PubChem Substance ID:
24846576
UNSPSC Code:
12352100
EC Number:
207-286-8
MDL number:
MFCD00001917

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

4-Fluorophenylacetonitrile, 99%

InChI key

JHQBLYITVCBGTO-UHFFFAOYSA-N

InChI

1S/C8H6FN/c9-8-3-1-7(2-4-8)5-6-10/h1-4H,5H2

SMILES string

Fc1ccc(CC#N)cc1

assay

99%

refractive index

n20/D 1.5002 (lit.)

bp

119-120 °C/18 mmHg (lit.)

density

1.126 g/mL at 25 °C (lit.)

functional group

fluoro
nitrile

Quality Level

100

Looking for similar products? Visit Product Comparison Guide

Related Categories

Biochem/physiol Actions

4-Fluorophenylacetonitrile undergoes biotransformation to 4-Fluorophenylacetic acid by marine fungi, Aspergillus sydowii Ce19.

General description

4-Fluorophenylacetonitrile is starting reagent in the synthesis of 1-Alkyl-N-[2-ethyl-2-(4-fluorophenyl)butyl]piperidine-4-carboxamide derivatives.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

226.4 °F - closed cup

flash_point_c

108 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
STBG3896V
STBG2743V
S60108V
STBC0499V
STBB9199V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Susumu Watanuki et al.
Bioorganic & medicinal chemistry, 19(18), 5628-5638 (2011-08-31)
We synthesized and evaluated inhibitory activity against T-type Ca(2+) channels for a series of 1-alkyl-N-[2-ethyl-2-(4-fluorophenyl)butyl]piperidine-4-carboxamide derivatives. Structure-activity relationship studies have revealed that dialkyl substituents at the benzylic position play an important role in increasing inhibitory activity. Oral administration of N-[2-ethyl-2-(4-fluorophenyl)butyl]-1-(2-phenylethyl)piperidine-4-carboxamide
Julieta Rangel de Oliveira et al.
Marine biotechnology (New York, N.Y.), 15(1), 97-103 (2012-07-14)
Marine fungi belonging to the genera Aspergillus, Penicillium, Cladosporium, and Bionectria catalyzed the biotransformation of phenylacetonitrile to 2-hydroxyphenylacetic acid. Eight marine fungi, selected and cultured with phenylacetonitrile in liquid mineral medium, catalyzed it quantitative biotransformation to 2-hydroxyphenylacetic acid. In this

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service