105481
1,3-Diphenylisobenzofuran
97%
Synonym(s):
1,3-Diphenyl-2-benzofuran, 2,5-Diphenyl-3,4-benzofuran
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About This Item
Empirical Formula (Hill Notation):
C20H14O
CAS Number:
Molecular Weight:
270.32
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
226-808-5
Beilstein/REAXYS Number:
199922
MDL number:
Assay:
97%
Form:
solid
InChI key
ZKSVYBRJSMBDMV-UHFFFAOYSA-N
InChI
1S/C20H14O/c1-3-9-15(10-4-1)19-17-13-7-8-14-18(17)20(21-19)16-11-5-2-6-12-16/h1-14H
SMILES string
c1ccc(cc1)-c2oc(-c3ccccc3)c4ccccc24
assay
97%
form
solid
mp
128-130 °C (lit.)
functional group
phenyl
Quality Level
Related Categories
General description
1,3-Diphenylisobenzofuran is a fluorescent dye.1,3-Diphenylisobenzofuran is the model compound in studies of singlet fission.
Application
1,3-Diphenylisobenzofuran(DPBF) was used as a fluorescent probe for detection of superoxide anion radical (O2−) inside the membrane lipid layer by DPBF fluorescence quenching method. 1,3-Diphenylisobenzofuran(DPBF) was used as quencher during the photoinactivation of TA-3 mouse mammary carcinoma cells containing hematoporphyrin. 1,3-Diphenylisobenzofuran(DPBF) was used to study the single crystal molecular structure and solution photophysical properties of DPBF.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Diana Zaharie-Butucel et al.
Journal of colloid and interface science, 552, 218-229 (2019-05-28)
Significant efforts are currently being funneled into the improvement of therapeutic outcomes in cancer by designing hybrid nanomaterials that synergistically combine chemotherapeutic abilities and near-infrared (NIR) light-activated photothermal (PTT) and photodynamic (PDT) activity. Herein, a nanotherapeutic platform is specifically designed
T Ohyashiki et al.
Biochimica et biophysica acta, 1421(1), 131-139 (1999-11-16)
Utilization of a fluorescence dye, 1,3-diphenylisobenzofuran (DPBF) as a detector of superoxide anion radical (O2*-) was examined. The fluorescence intensity of DPBF incorporated in phospholipid liposomes consisting of phosphatidylcholine (PC) and phosphatidylserine (PS) is effectively quenched by incubation with xanthine/xanthine
K R Weishaupt et al.
Cancer research, 36(7 PT 1), 2326-2329 (1976-07-01)
Singlet oxygen, a metastable state of normal triplet oxygen, has been identified as the cytotoxic agent that is probably responsible for in vitro inactivation of TA-3 mouse mammary carcinoma cells following incorporation of hematoporphyrin and exposure to red light. This
Xumei Ouyang et al.
Biomaterials science, 8(4), 1160-1170 (2019-12-19)
Mesenchymal stem cell (MSC)-based biomimetic delivery has been actively explored for drug accumulation and penetration into tumors by taking advantage of the tumor-tropic and penetration properties of MSCs. In this work, we further demonstrated the feasibility of MSC-mediated nano drug
Meng Duan et al.
Nanoscale, 11(39), 18426-18435 (2019-10-03)
This work explored the application of matrix metalloproteinase 2-targeted superparamagnetic nanoprobes for magnetic resonance imaging (MRI), near infrared (NIR) fluorescence imaging and photodynamic therapy of tumors. PEG, PAMAM (G5) and matrix metalloproteinase 2 (MMP2) were attached to the surface of
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