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About This Item
Linear Formula:
C6H5CONHC6H5
CAS Number:
Molecular Weight:
197.23
EC Number:
202-292-7
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Colour Index Number:
42095
Beilstein/REAXYS Number:
1102980
Assay:
98%
Form:
solid
InChI key
ZVSKZLHKADLHSD-UHFFFAOYSA-N
InChI
1S/C13H11NO/c15-13(11-7-3-1-4-8-11)14-12-9-5-2-6-10-12/h1-10H,(H,14,15)
SMILES string
O=C(Nc1ccccc1)c2ccccc2
assay
98%
form
solid
bp
117 °C/10 mmHg (lit.)
Quality Level
Gene Information
human ... EPHX2(2053)
mouse ... Ephx2(13850)
solubility
H2O: insoluble, diethyl ether: slightly soluble
functional group
amide, phenyl
Related Categories
General description
Benzanilide undergoes diarylation with aryl triflates or bromides in the presence of a palladium-based catalyst system to form corresponding N-(2,6-diarylbenzoyl)anilines. It is used in manufacture of dyes and perfumes.
Application
Benzanilide was used to study the influence of β-cyclodextrin on photorearrangement of acetanilide, benzanilide and ethyl phenyl carbonate. It was used as amide model compound to study the reaction between the amide and epoxy.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Dritan Hasa et al.
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Dodeca-2E,4E,8Z,10E/Z-tetraenoic isobutylamide (tetraene) is the main component of Echinacea angustifolia DC. lipophilic extract, the bioavailability and immunomodulatory effect after oral administration in soft gel capsules in healthy volunteers of which we have already demonstrated. In the present work, we assessed
Katherine A Rawls et al.
Bioorganic & medicinal chemistry letters, 19(24), 6851-6854 (2009-11-06)
The development of low muM inhibitors of the Mycobacterium tuberculosis phosphatase PtpA is reported. The most potent of these inhibitors (K(i)=1.4+/-0.3 microM) was found to be selective when tested against a panel of human tyrosine and dual-specificity phosphatases (11-fold vs
Gerda Brunhofer et al.
Bioorganic & medicinal chemistry, 19(2), 994-1001 (2010-12-28)
A series of dithiobenzanilide derivatives was synthesized and each compound was evaluated for its ability to reduce KCl-induced contractions of smooth muscle preparations of the guinea pig. Starting from a recent publication describing benzanilide derivatives as antispasmodic agents, structure-activity guided
Joanne V Allen et al.
Bioorganic & medicinal chemistry letters, 21(18), 5224-5229 (2011-08-13)
A directed screen of a relatively small number of compounds, selected for kinase ATP pocket binding potential, yielded a novel series of hit compounds (1). Hit explosion on two binding residues identified compounds 27 and 43 as the best leads
Synthesis of 2-arylbenzoxazoles by copper-catalyzed intramolecular oxidative C-O coupling of benzanilides.
Satoshi Ueda et al.
Angewandte Chemie (International ed. in English), 47(34), 6411-6413 (2008-07-12)
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