108227
Benzanilide
98%
Synonym(s):
N-Benzoylaniline, N-Phenylbenzamide
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About This Item
Linear Formula:
C6H5CONHC6H5
CAS Number:
Molecular Weight:
197.23
EC Number:
202-292-7
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Colour Index Number:
42095
Beilstein/REAXYS Number:
1102980
Assay:
98%
Form:
solid
InChI key
ZVSKZLHKADLHSD-UHFFFAOYSA-N
InChI
1S/C13H11NO/c15-13(11-7-3-1-4-8-11)14-12-9-5-2-6-10-12/h1-10H,(H,14,15)
SMILES string
O=C(Nc1ccccc1)c2ccccc2
assay
98%
form
solid
bp
117 °C/10 mmHg (lit.)
Quality Level
Gene Information
human ... EPHX2(2053)
mouse ... Ephx2(13850)
solubility
H2O: insoluble, diethyl ether: slightly soluble
functional group
amide, phenyl
Related Categories
General description
Benzanilide undergoes diarylation with aryl triflates or bromides in the presence of a palladium-based catalyst system to form corresponding N-(2,6-diarylbenzoyl)anilines. It is used in manufacture of dyes and perfumes.
Application
Benzanilide was used to study the influence of β-cyclodextrin on photorearrangement of acetanilide, benzanilide and ethyl phenyl carbonate. It was used as amide model compound to study the reaction between the amide and epoxy.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Dritan Hasa et al.
Pharmaceutics, 12(11) (2020-11-20)
Dodeca-2E,4E,8Z,10E/Z-tetraenoic isobutylamide (tetraene) is the main component of Echinacea angustifolia DC. lipophilic extract, the bioavailability and immunomodulatory effect after oral administration in soft gel capsules in healthy volunteers of which we have already demonstrated. In the present work, we assessed
Thermodynamic interactions of a cis and trans benzanilide with Escherichia coli bacterial membranes.
Sarah R Dennison et al.
European biophysics journal : EBJ, 41(8), 687-693 (2012-07-12)
The activity of a membrane interactive cis and trans benzanilide against Escherichia coli membrane mimics was investigated using Langmuir monolayers. It was found that in the presence of E. coli lipid mix monolayers, cis-benzanilide induced maximal surface pressure changes of
Regioselective arylation of benzanilides with aryl triflates or bromides under palladium catalysis.
Kametani Y, et al.
Tetrahedron Letters, 41(15), 2655-2658 (2000)
Andrew K L Goey et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(1), 41-48 (2010-12-03)
Echinacea purpurea is one of the most popular herbal medicines and is known for its immunostimulatory effects. Alkylamides are the main lipophilic components of E. purpurea that contribute to its pharmacological actions. For quantification in human plasma of one of
Anna M Kauppi et al.
Bioorganic & medicinal chemistry, 15(22), 6994-7011 (2007-09-14)
Compound 1, 2-(benzo[1,2,5]thiadiazole-4-sulfonylamino)-5-chloro-N-(3,4-dichloro-phenyl)-benzamide, was identified as a putative type III secretion inhibitor in Yersinia, and the compound thus has a potential to be used to prevent or treat bacterial infections. A set of seven analogues was synthesized and evaluated in
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