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109266

Aminoguanidine bicarbonate

97%

Synonym(s):

Aminoguanidine hydrogencarbonate, Guanylhydrazine hydrogencarbonate

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About This Item

Linear Formula:
NH2NHC(=NH)NH2 · H2CO3
CAS Number:
2582-30-1
Molecular Weight:
136.11
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24846902
EC Number:
219-956-7
Beilstein/REAXYS Number:
3569869
MDL number:
MFCD00012949
Assay:
97%
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Quality Level

100

assay

97%

mp

170-172 °C (dec.) (lit.)

solubility

H2O: soluble 2.7 g/L at 20 °C, H2O: soluble 3.3 g/L at 30 °C

functional group

amine, hydrazine

SMILES string

OC(O)=O.NNC(N)=N

InChI

1S/CH6N4.CH2O3/c2-1(3)5-4;2-1(3)4/h4H2,(H4,2,3,5);(H2,2,3,4)

InChI key

OTXHZHQQWQTQMW-UHFFFAOYSA-N

Application

Aminoguanidine bicarbonate was used to study the effect of addition of polyamines to rat embryo cell cultures infected with adenovirus type 5.

Biochem/physiol Actions

Aminoguanidine bicarbonate protects the cells infected with adenovirus from chromosomal damage. Aminoguanidine is a specific and highly effective inhibitor of diamine oxidase present in fetal calf serum.

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

hcodes

H317,H411

Hazard Classifications

Aquatic Chronic 2 - Skin Sens. 1

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

危险化学品

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Certificates of Analysis (COA)

Lot/Batch Number
SDBB8315
SDBB5539
SDBB2524
STBL4091
STBL2325

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W A Gahl et al.
Chemico-biological interactions, 22(1), 91-98 (1978-07-01)
The inhibitory effect of the polyamines, spermidine and spermine, on the proliferation of human fibroblasts in culture was found to be reversed by the addition of aminoguanidine (AM), a specific and highly effective inhibitor of diamine oxidase (DAO) present in
Sebastiano Intagliata et al.
Antioxidants (Basel, Switzerland), 10(1) (2020-12-31)
Resveratrol (RSV) is well known for its many beneficial activities, but its unfavorable physicochemical properties impair its effectiveness after systemic and topical administration; thus, several strategies have been investigated to improve RSV efficacy. With this aim, in this work, we
Paola Mirra et al.
Biochimica et biophysica acta, 1863(2), 440-449 (2016-11-20)
Methylglyoxal (MGO) is a reactive dicarbonyl produced as by-product of glycolysis, and its formation is heightened in hyperglycaemia. MGO plasma levels are two-fold to five-fold increased in diabetics and its accumulation promotes the progression of vascular complications. Impairment of endothelium-derived
View All Related Papers

Global Trade Item Number

SKUGTIN
109266-500G04061838688156
109266-100G04061838688149