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Merck
CN

11268

Tetraethylammonium bicarbonate

≥95.0% (T), solid

Synonym(s):

Tetraethylammonium hydrogen carbonate

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About This Item

Linear Formula:
(CH3CH2)4N(HCO3)
CAS Number:
Molecular Weight:
191.27
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.22
MDL number:
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Product Name

Tetraethylammonium bicarbonate, 90.0-110.0% (T)

Quality Level

assay

90.0-110.0% (T)

form

solid

reaction suitability

core: ammonium

SMILES string

OC([O-])=O.CC[N+](CC)(CC)CC

InChI

1S/C8H20N.CH2O3/c1-5-9(6-2,7-3)8-4;2-1(3)4/h5-8H2,1-4H3;(H2,2,3,4)/q+1;/p-1

InChI key

XUBMPLUQNSSFHO-UHFFFAOYSA-M

Application

Tetraethylammonium bicarbonate is used:
  • In the synthesis of carbamate esters from amines.
  • As a precipitant for synthesizing Cu/ZnO catalysts via coprecipitation method.
  • As an alternative to the traditional phase-transfer system in [18F]radiofluorinations for preventing microreactor blockages.
  • To promote carboxylation of secondary carboxamides bearing a leaving group at the α-position in the synthesis of oxazolidine-2,4-diones.



pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Evaluation of tetraethylammonium bicarbonate as a phase-transfer agent in the formation of [18F] fluoroarenes.
Reed CD, et al.
Journal of Fluorine Chemistry, 143(4), 231-237 (2012)
Use of tetraethylammonium bicarbonate as a precipitation agent on the preparation of coprecipitated Cu/ZnO catalysts.
Jeong C, et al.
Applied Catalysis A: General, 541(4), 35-41 (2017)
Monica M Schroll et al.
Journal of the American Society for Mass Spectrometry, 29(10), 2012-2022 (2018-07-19)
Short-term glucose starvation prior to chemotherapy has the potential to preferentially weaken cancer cells, making them more likely to succumb to treatment, while protecting normal cells. In this study, we used 3D cell cultures of colorectal cancer and assessed the



Global Trade Item Number

SKUGTIN
307807-500G04061826673898
636967-250G04061833607107
307807-100G04061826673881
636967-25G04061832723310
594849-25G04061832643984
11268-25G-F04061833365960