115169
Tetramethylthiourea
98%
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About This Item
Linear Formula:
(CH3)2NCSN(CH3)2
CAS Number:
Molecular Weight:
132.23
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
220-488-0
Beilstein/REAXYS Number:
1744916
MDL number:
Assay:
98%
Form:
solid
Product Name
Tetramethylthiourea, 98%
InChI key
MNOILHPDHOHILI-UHFFFAOYSA-N
InChI
1S/C5H12N2S/c1-6(2)5(8)7(3)4/h1-4H3
SMILES string
CN(C)C(=S)N(C)C
assay
98%
form
solid
bp
245 °C (lit.)
mp
75-77 °C (lit.)
storage temp.
2-8°C
Quality Level
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Application
Tetramethylthiourea forms BF3 adduct with tetramethylselenourea.
General description
Tetramethylthiourea molecule shows crystallographic two-fold symmetry with weak hydrogen bond packing, which connects the molecules to form layers.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Y Usson et al.
Journal of neurocytology, 17(5), 639-648 (1988-10-01)
The proliferation of Schwann cells in the sciatic nerve of chick was studied from day 11 to day 27 of development in control and thyroid-deficient embryos. Hypothyroidism was induced by tetramethylthiourea injection on days 8 and 19 of incubation. The
Allen Mambanda et al.
Dalton transactions (Cambridge, England : 2003), 39(15), 3595-3608 (2010-04-01)
The rate of displacement of the aqua ligands by three neutral nucleophiles (Nu) of different steric demands, namely thiourea (tu), N,N'-dimethylthiourea (dmtu) and N,N,N',N'-tetramethylthiourea (tmtu) and an anionic nucleophile (I(-)) in complexes of the form [{Pt(H(2)O)}(2)(N,N,N',N'-tetrakis(2-pyridylmethyl)-N(CH(2))(n)N](CF(3)SO(3))(4), n = 2 (En);
A Shukla et al.
Cancer research, 61(5), 1791-1795 (2001-03-31)
Crystalline silica has been classified as a group 1 human carcinogen in the lung. However, its mechanisms of action on pulmonary epithelial cells which give rise to lung cancers are unclear. Using a nontransformed alveolar type II epithelial cell line
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Toxicology and applied pharmacology, 208(1), 37-45 (2005-09-17)
Air pollution particles (PM) are known to elicit an acute inflammatory response in vivo that is mediated in part through PM-induced activation of the NF-kappaB signaling pathway. Many of the details of this process and particularly where in the cell
T Sakamoto et al.
The American journal of physiology, 276(6 Pt 1), C1391-C1397 (1999-06-11)
Obesity is associated with hyperinsulinemia and elevated concentrations of tumor necrosis factor-alpha (TNF-alpha) in adipose tissue. TNF-alpha has been implicated as an inducer of the synthesis of plasminogen activator inhibitor-1 (PAI-1), the primary physiological inhibitor of fibrinolysis, mediated by plasminogen
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