115673
2-Bromo-3′-methoxyacetophenone
98%
Synonym(s):
3′-Methoxyphenacyl bromide
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Linear Formula:
CH3OC6H4COCH2Br
CAS Number:
Molecular Weight:
229.07
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
225-666-1
MDL number:
Assay:
98%
Product Name
2-Bromo-3′-methoxyacetophenone, 98%
InChI key
IOOHBIFQNQQUFI-UHFFFAOYSA-N
InChI
1S/C9H9BrO2/c1-12-8-4-2-3-7(5-8)9(11)6-10/h2-5H,6H2,1H3
SMILES string
COc1cccc(c1)C(=O)CBr
assay
98%
mp
60-62 °C (lit.)
functional group
bromo
ketone
storage temp.
2-8°C
Quality Level
Related Categories
Application
2-bromo-3′-methoxyacetophenone, an alkylating agent, has been used to stabilize clopidogrel active metabolite (AM) in human plasma. It has also been used in the derivatisation of active metabolites in blood to ensure its stability during sample processing and storage.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
target_organs
Respiratory system
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Nagy A Farid et al.
Rapid communications in mass spectrometry : RCM, 21(2), 169-179 (2006-12-13)
Two fast and sensitive liquid chromatography/tandem mass spectrometry (LC/MS/MS)-based bioanalytical assays were developed and validated to quantify the active and three inactive metabolites of prasugrel. Prasugrel is a novel thienopyridine prodrug that is metabolized to the pharmacologically active metabolite in
Jin-Zi Ji et al.
Biochemical pharmacology, 183, 114313-114313 (2020-11-03)
Variability in P-glycoprotein (P-gp) efflux transporting activity was supposed to be involved in altered intestinal absorption and bioavailability of clopidogrel in patients; however, reliable evidence is still lacking. In this study, we sought to determine whether P-gp could play an
Hongwei Yao et al.
Biochemical pharmacology, 180, 114142-114142 (2020-07-13)
Patients with diabetic mellitus tend to have a poor response to clopidogrel (Clop) due to reduced generation of active metabolite (Clop-AM). However, the underlying mechanism is not elucidated. A type 2 diabetic mellitus (T2DM) rat model was established by combining
Bogumił Ramotowski et al.
Thrombosis and haemostasis, 120(3), 449-456 (2020-01-16)
Cigarette smoking is associated with enhanced clopidogrel effect and platelet inhibition. However, the effect of smoking cessation on clopidogrel pharmacokinetics (PK) and pharmacodynamics (PD) is unknown. We aimed to determine the effect of smoking cessation, confirmed by cotinine measurement, on
Makoto Takahashi et al.
Journal of pharmaceutical and biomedical analysis, 48(4), 1219-1224 (2008-10-03)
A quantitative method for the determination of clopidogrel active metabolite (AM) in human plasma was developed and validated using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Clopidogrel AM contains a thiol group, thus requiring stabilization in biological samples. The alkylating reagent 2-bromo-3'-methoxyacetophenone
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service