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116092

Triethyl 4-phosphonocrotonate, mixture of isomers

technical grade, 90%

Synonym(s):

4-(Diethoxyphosphinyl)-2-butenoic acid ethyl ester, 4-Phosphonocrotonic acid triethyl ester

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About This Item

Linear Formula:
(C2H5O)2P(O)CH2CH=CHCO2C2H5
CAS Number:
10236-14-3
Molecular Weight:
250.23
NACRES:
NA.22
PubChem Substance ID:
24847263
UNSPSC Code:
12352108
MDL number:
MFCD00009192
Assay:
90%
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grade

technical grade

Quality Segment

100

assay

90%

reaction suitability

reaction type: C-C Bond Formation

refractive index

n20/D 1.455 (lit.)

bp

135 °C/0.4 mmHg (lit.)

density

1.128 g/mL at 25 °C (lit.)

SMILES string

CCOC(=O)\C=C\CP(=O)(OCC)OCC

InChI

1S/C10H19O5P/c1-4-13-10(11)8-7-9-16(12,14-5-2)15-6-3/h7-8H,4-6,9H2,1-3H3/b8-7+

InChI key

LXLODBXSCRTXFG-BQYQJAHWSA-N

Application

Reactant for:
  • Iminodipropionic acid as a leaving group for DNA polymerization by HIV-1 reverse transcriptase
  • Stereoselective preparation of C1-C19 fragment of macrolide antibiotic aplyronine A using diastereoselective Nozaki-Hiyama-Kishi coupling reactions
  • Orally bioavailable GPR40 agonist synthesis
  • Synthesis of fluoroketone inhibitors of group VIA calcium-independent phospholipase A2
  • Preaparation of mGlu4R agonists
  • Dearomatizing cyclization of nicotinyl-substituted esters and ketones

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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