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Merck
CN

117455

p-Toluenesulfonyl fluoride

98%

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About This Item

Linear Formula:
CH3C6H4SO2F
CAS Number:
Molecular Weight:
174.19
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
207-238-6
MDL number:
Assay:
98%
Form:
solid
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InChI key

IZZYABADQVQHLC-UHFFFAOYSA-N

InChI

1S/C7H7FO2S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3

SMILES string

Cc1ccc(cc1)S(F)(=O)=O

assay

98%

form

solid

reaction suitability

reaction type: click chemistry

bp

112 °C/16 mmHg (lit.)

mp

41-42 °C (lit.)

Quality Level

General description

p-Toluenesulfonyl fluoride is a peroxygen bleach activator and is also useful in the treatment of Alzheimer′s disease.

Application

p-Toluenesulfonyl fluoride was used to study the DNS polymerase from spinach leaf extracts. It was used in isolation and separation of Pseudomonas aeruginosa membranes by density sucrose gradient centrifugation.
Protease inhibitor.

wgk

WGK 3

pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

flash_point_f

222.8 °F - closed cup

flash_point_c

106 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Jinkui Yang et al.
Biotechnology letters, 27(15), 1123-1128 (2005-09-01)
Lecanicillium psalliotae produced an extracellular protease (Ver112) which was purified to apparent homogeneity giving a single band on SDS-PAGE with a molecular mass of 32 kDa. The optimum activity of Ver112 was at pH 10 and 70 degrees C (over
Tsuyoshi Fujita et al.
Cellular signalling, 17(2), 167-175 (2004-10-21)
In this study, we examined the mechanism by which CD38 cleavage is regulated through the mitogen-activated protein (MAP) kinases after stimulation by fMLP and interleukin-8 (IL-8) in neutrophils. Both fMLP and IL-8 increased chemotaxis and decreased CD38 protein in neutrophils
Tomonori Kaneko et al.
Protein science : a publication of the Protein Society, 14(2), 558-565 (2005-01-06)
Growth-limiting stresses in bacteria induce the general stress response to protect the cells against future stresses. Energy stress caused by starvation conditions in Bacillus subtilis is transmitted to the sigma(B) transcription factor by stress-response regulators. RsbP, a positive regulator, is
Nobuyuki Shibata et al.
FEMS microbiology letters, 256(1), 137-144 (2006-02-21)
Lipophilic Malassezia species may induce catheter-associated sepsis in premature neonates and immunocompromised patients receiving parenteral lipid emulsions. To assess the participation of lipolytic enzymes in the pathogenesis of this yeast, we cloned a gene encoding the enzyme. A lipolytic enzyme
Pyo-Jam Park et al.
Journal of biochemistry and molecular biology, 35(6), 576-582 (2002-12-10)
Collagenase from the internal organs of a mackerel was purified using acetone precipitation, ion-exchange chromatography on a DEAE-Sephadex A-50, gel filtration chromatography on a Sephadex G-100, ion-exchange chromatography on DEAE-Sephacel, and gel filtration chromatography on a Sephadex G-75 column. The

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