123072
Luminol
97%
Synonym(s):
3-Aminophthalhydrazide, 5-Amino-2,3-dihydro-1,4-phthalazinedione
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About This Item
Empirical Formula (Hill Notation):
C8H7N3O2
CAS Number:
Molecular Weight:
177.16
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
EC Number:
208-309-4
Beilstein/REAXYS Number:
383929
MDL number:
Quality Level
assay
97%
mp
>300 °C (lit.)
SMILES string
Nc1cccc2C(=O)NNC(=O)c12
InChI
1S/C8H7N3O2/c9-5-3-1-2-4-6(5)8(13)11-10-7(4)12/h1-3H,9H2,(H,10,12)(H,11,13)
InChI key
HWYHZTIRURJOHG-UHFFFAOYSA-N
General description
Luminol is a very efficient and commonly used chemiluminiscent compound in condensed phase. When basic solutions of luminol containing oxygen are treated with an oxidizing agent, light is produced. Oxidising agents capable of initiating this particular reaction are Nitrogen dioxide, PAN, hydrogen peroxide, ozone and other atmospheric oxidants.
Application
Luminol has been used in a protocol to study the immune-related responses in Arabidopsis thaliana via luminol/peroxidase-based assay.
- As a chemiluminiscent substance. Used to measure opsonic and phagocytic function.
- As a biological sensor. Used to detect the polymorphonuclear leukocytes (PMNL) response in a patient with a myeloperoxidase (MPO) deficiency.
- Used as a forensic test for blood.
Features and Benefits
- Very effective chemiluminiscent compound.
- Can detect sub-part per billion levels of metal ions with simple and inexpensive instrumentation.
Used for chemiluminescence analysis of, for example, metal cations, blood, and glucococorticoids.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
signalword
Warning
hcodes
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Articles
Graphene is the building block for carbon nanomaterials with different dimensionalities.
C S Easmon et al.
Immunology, 41(1), 67-74 (1980-09-01)
Luminol-dependent chemiluminescence produced by peripheral blood phagocytic cells was measured using a light detecting instrument, the Luminometer 1250 (LKB Wallac). Although less sensitive than liquid scintillation counters, the Luminometer can measure chemiluminescence effectively and detect experimentally induced and clinical variations
Mechanism of cobalt catalysis of luminol chemiluminescence
Burdo, Timothy G., and W. Rudolf Seitz
Analytical Chemistry, 47, 1639-1643 (1975)
T I Quickenden et al.
Luminescence : the journal of biological and chemical luminescence, 16(4), 295-298 (2001-08-21)
A wide range of domestic and industrial substances that might be mistaken for haemoglobin in the forensic luminol test for blood were examined. The substances studied were in the categories of vegetable or fruit pulps and juices; domestic and commercial
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 123072-2.5G | 04061835532117 |
| 123072-5G | 04061835561353 |
| 123072-25G | 04061835561346 |