123129
2-Aminothiazole
97%
Synonym(s):
2-Thiazolamine
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About This Item
Empirical Formula (Hill Notation):
C3H4N2S
CAS Number:
Molecular Weight:
100.14
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
202-511-6
Beilstein/REAXYS Number:
105738
MDL number:
Assay:
97%
Quality Segment
assay
97%
mp
91-93 °C (lit.)
solubility
1 M HCl: soluble 50 mg/mL, clear (dark yellow-brown)
SMILES string
Nc1nccs1
InChI
1S/C3H4N2S/c4-3-5-1-2-6-3/h1-2H,(H2,4,5)
InChI key
RAIPHJJURHTUIC-UHFFFAOYSA-N
Application
2-Aminothiazole was used in the synthesis of 2-aminothiazole-modified silica gel. It was used in Ulmann coupling with 2-chlorobenzoic acids mediated by ultrasonic irradiation.
Biochem/physiol Actions
2-Aminothiazoles are potent cyclin-dependent kinase 5 inhibitors and are therapeutic agents for the treatment of Alzheimer′s disease and other neurodegenerative disorders.
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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