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Merck
CN

128791

5-Quinolinol

99%

Synonym(s):

5-Hydroxyquinoline

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About This Item

Empirical Formula (Hill Notation):
C9H7NO
CAS Number:
Molecular Weight:
145.16
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
209-428-4
Beilstein/REAXYS Number:
114514
MDL number:
Assay:
99%
Form:
solid
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assay

99%

form

solid

mp

223-226 °C (lit.)

SMILES string

Oc1cccc2ncccc12

InChI

1S/C9H7NO/c11-9-5-1-4-8-7(9)3-2-6-10-8/h1-6,11H

InChI key

GYESAYHWISMZOK-UHFFFAOYSA-N

Application

5-Quinolinol (5-Hydroxyquinoline) was used as an internal standard in the reaction to measure morphine concentration in serum or plasma. It was also used as a lipophilic chelator and it decreased the rate of deoxygenation.


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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H Vandenberghe et al.
Therapeutic drug monitoring, 4(3), 307-314 (1982-01-01)
In this report we describe a rapid and sensitive micromethod using high performance liquid chromatography (HPLC) with electrochemical detection (ED) to measure morphine concentration in serum or plasma. The separation of morphine and the internal standard 5-hydroxyquinoline, from interfering compounds
M Hollstein et al.
Journal of the National Cancer Institute, 60(2), 405-410 (1978-02-01)
Quinoline, a hepatocarcinogen in rats, and 23 quinoline derivatives were tested for mutagenic activity with the Ames Salmonella typhimurium assay. Quinoline, 5-hydroxyquinoline, and 8-hydroxyquinoline were mutagenic in strain TA 100 when Aroclor 1254-induced rat (male outbred Sprague-Dawley) liver homogenate was
R Deslauriers et al.
Biochimica et biophysica acta, 886(3), 319-326 (1986-05-29)
A spectrophotometric assay has been devised to measure oxygen consumption non-invasively in intact murine red cells parasitized by Plasmodium berghei. The method uses oxyhemoglobin in the erythrocytes both as a source of oxygen and as an indicator of oxygen consumption.



Global Trade Item Number

SKUGTIN
128791-1G04061826256923