129585
Maleimide
99%
Synonym(s):
2,5-Pyrroledione
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About This Item
Empirical Formula (Hill Notation):
C4H3NO2
CAS Number:
Molecular Weight:
97.07
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
208-787-4
Beilstein/REAXYS Number:
106910
MDL number:
Assay:
99%
Form:
powder
Quality Level
assay
99%
form
powder
mp
91-93 °C (lit.)
functional group
maleimide
SMILES string
O=C1NC(=O)C=C1
InChI
1S/C4H3NO2/c6-3-1-2-4(7)5-3/h1-2H,(H,5,6,7)
InChI key
PEEHTFAAVSWFBL-UHFFFAOYSA-N
General description
Maleimide (2,5-Pyrroledione) is a new nanoparticle surface functional group which favors easy conjugation with cell penetration peptides. The conjugation is enabled via click chemistry to preserve its biofunctions.
Maleimide is used as a dienophile in Diels Alder reaction for the synthesis of macromolecules.
Maleimide is used as a dienophile in Diels Alder reaction for the synthesis of macromolecules.
Application
Rhodium-catalyzed conjugate arylation with arylboronic acids.
The maleimide-functionalized silica beads were used to immobilize the bovine serum albumin (BSA)-boronic acid (BA) conjugates.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Tetrahedron Letters, 48, 4413-4413 (2007)
The furan/maleimide Diels--Alder reaction: A versatile click--unclick tool in macromolecular synthesis
Gandini A.
Progress in Polymer Science, 38, 1-29 (2013)
Guangxue Feng et al.
Small (Weinheim an der Bergstrasse, Germany), 10(6), 1212-1219 (2013-12-18)
Single-chain conjugated polymer (CP) dots embedded nanoparticles (NPs) bearing cell penetration peptide (TAT) as surface ligands are synthesized for long term cancer cell tracing applications. The CPNPs are fabricated by matrix-encapsulation method and the embedded CPs can be modulated into
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 129585-2G | 04061838726391 |
| 129585-25G | 04061838726384 |
| 129585-10G | 04061838726377 |