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Merck
CN

136565

N-(3-Aminopropyl)-2-pyrrolidinone

technical grade

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About This Item

Empirical Formula (Hill Notation):
C7H14N2O
CAS Number:
Molecular Weight:
142.20
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
231-632-7
MDL number:
Form:
liquid
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grade

technical grade

Quality Level

form

liquid

impurities

2% 2-pyrrolidinone

refractive index

n20/D 1.5 (lit.)

bp

120-123 °C/1 mmHg (lit.)

density

1.014 g/mL at 25 °C (lit.)

functional group

amine

SMILES string

NCCCN1CCCC1=O

InChI

1S/C7H14N2O/c8-4-2-6-9-5-1-3-7(9)10/h1-6,8H2

InChI key

HJORCZCMNWLHMB-UHFFFAOYSA-N

General description

N-(3-Aminopropyl)-2-pyrrolidinone (PYR) conjugates (VPA-PYR) of valproic acid (VA) have been investigated for their anticonvulsant activity in mice. It is the γ-lactam form of isoputreanine.

Application

N-(3-Aminopropyl)-2-pyrrolidinone was used in the simultaneous determination of total polyamines and three of their non−α− amino acid metabolites in urine by capillary gas-chromatographic method with nitrogen-phosphorus detection.

Other Notes

Contains varying amounts of 1,5-diazabicyclo[4.3.0]non-5-ene (cat. no. 136581)


pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter



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N Seiler et al.
The Biochemical journal, 208(1), 189-197 (1982-10-15)
A high-pressure-liquid-chromatographic method suitable for the separation and sensitive detection of putreanine and isoputreanine is described. This method allowed us to study the formation of the metabolites of the oxidative deamination of spermidine and N1-acetylspermidine. Administration of spermidine trishydrochloride to
N Seiler et al.
The International journal of biochemistry, 15(7), 907-915 (1983-01-01)
Normal human and rat urine contain N-(3-aminopropyl)pyrrolidin-2-one. This compound was identified by its chromatographic behaviour on a reversed phase column, by thin-layer chromatography of its dansyl derivative, and by mass spectrometry. Evidence for the presence of conjugates of N-(3-aminopropyl)pyrrolidin-2-one in
Andre P Martinez et al.
Biomacromolecules, 18(6), 2000-2011 (2017-05-20)
A series of biodegradable drug delivery polymers with intrinsic multifunctionality have been designed and synthesized utilizing a polyphosphazene macromolecular engineering approach. Novel water-soluble polymers, which contain carboxylic acid and pyrrolidone moieties attached to an inorganic phosphorus-nitrogen backbone, were characterized by



Global Trade Item Number

SKUGTIN
679399-1G04061825934969
1359437-20MG04061833851050
PHR2432-50MG04065265026604
Y000194804061835123216
136565-100G04061837871580
136565-25G04061837871597
136565-5G04061838731340