Skip to Content
Merck
CN

136891

cis-1,2,3,6-Tetrahydrophthalic anhydride

95%

Synonym(s):

cis-4-Cyclohexene-1,2-dicarboxylic anhydride

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C8H8O3
CAS Number:
Molecular Weight:
152.15
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
213-308-7
Beilstein/REAXYS Number:
82341
MDL number:
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


vapor density

5.2 (vs air)

Quality Level

vapor pressure

<0.01 mmHg ( 20 °C)

assay

95%

form

flakes

mp

97-103 °C (lit.)

SMILES string

[H][C@@]12CC=CC[C@]1([H])C(=O)OC2=O

InChI

1S/C8H8O3/c9-7-5-3-1-2-4-6(5)8(10)11-7/h1-2,5-6H,3-4H2/t5-,6+

InChI key

KMOUUZVZFBCRAM-OLQVQODUSA-N

Application

cis-1,2,3,6-Tetrahydrophthalic anhydride (THPA) can be used as:
  • A curing agent for epoxides.
  • A chemical modifier in the modification of polystyrene via Friedel-Crafts acylation for enhancing the thermal stability of the polymer.
  • A reactant for the synthesis of cis-tetrahydroisoindole-1,3-dione derivatives and cyclic diimides.



pictograms

Health hazardCorrosion

signalword

Danger

Hazard Classifications

Aquatic Chronic 3 - Eye Dam. 1 - Resp. Sens. 1 - Skin Sens. 1

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

312.8 °F - closed cup

flash_point_c

156 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library



Montmorillonite K-10 supported one-pot synthesis of some symmetric diimides and 3a, 4, 7, 7a-tetrahydroisoindole-1, 3-dione derivatives under solvent-free conditions using microwaves
Habibi D and Marvi O
J. Serb. Chem. Soc., 70(4), 579-583 (2005)
Chemical modification of polystyrene?IV. Electrophilic substitution of polystyrene with cis-1, 2, 3, 6 tetrahydrophthalic anhydride
Biswas M and Chatterjee S
European Polymer Journal, 19(4), 317-320 (1983)
Cong Zhang et al.
Journal of controlled release : official journal of the Controlled Release Society, 226, 193-204 (2016-02-21)
Stepwise pH-responsive nanoparticle system containing charge reversible pullulan-based (CAPL) shell and poly(β-amino ester) (PBAE)/poly(lactic-co-glycolic acid) (PLAG) core is designed to be used as carriers of paclitaxel (PTX) and combretastatin A4 (CA4) for combining antiangiogenesis and chemotherapy to treat hepatocellular carcinoma



Global Trade Item Number

SKUGTIN
136891-100G04061833595084
136891-1KG04061826714409