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Sigma-Aldrich

2-Ethyl-2-oxazoline

≥99%

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Synonym(s):
2-Ethyl-4,5-dihydrooxazole, 2-Ethyloxazoline
Empirical Formula (Hill Notation):
C5H9NO
CAS Number:
Molecular Weight:
99.13
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥99%

form

liquid

refractive index

n20/D 1.437 (lit.)

bp

128.4 °C (lit.)

mp

−62 °C (lit.)

density

0.982 g/mL at 25 °C (lit.)

SMILES string

CCC1=NCCO1

InChI

1S/C5H9NO/c1-2-5-6-3-4-7-5/h2-4H2,1H3

InChI key

NYEZZYQZRQDLEH-UHFFFAOYSA-N

General description

2-Ethyl-2-oxazoline undergoes cationic ring opening graft polymerization using tosylated cellulose nanowhisker as macroinitiator.

Application

2-Ethyl-2-oxazoline (EtOx) was used in synthesis of block copolymers of EtOx and styrene by cationic ring-opening polymerization and atom transfer radical polymerization.

Pictograms

FlameExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Flam. Liq. 3

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

84.2 °F - closed cup

Flash Point(C)

29 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

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Věra Mazánková et al.
Polymers, 12(11) (2020-11-19)
Polyoxazoline thin coatings were deposited on glass substrates using atmospheric pressure plasma polymerization from 2-ethyl-2-oxazoline vapours. The plasma polymerization was performed in dielectric barrier discharge burning in nitrogen at atmospheric pressure. The thin films stable in aqueous environments were obtained
Steffen Czich et al.
Molecules (Basel, Switzerland), 25(21) (2020-11-05)
The main task of tissue engineering (TE) is to reproduce, replicate, and mimic all kinds of tissues in the human body. Nowadays, it has been proven useful in TE to mimic the natural extracellular matrix (ECM) by an artificial ECM
Synthesis of poly (2-ethyl-2-oxazoline)-b-poly (styrene) copolymers via a dual initiator route combining cationic ring-opening polymerization and atom transfer radical polymerization.
Becer CR, et al.
Macromolecules, 41(14), 5210-5215 (2008)
Blaise L Tardy et al.
Biomacromolecules, 20(3), 1421-1428 (2019-02-23)
Metal-phenolic network (MPN) coatings have generated increasing interest owing to their biologically inspired nature, facile fabrication, and near-universal adherence, especially for biomedical applications. However, a key issue in biomedicine is protein fouling, and the adsorption of proteins on tannic acid-based
Mohsen Salmanpour et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 136, 104941-104941 (2019-05-29)
SN-38 is the active metabolite of irinotecan, an FDA-approved chemotherapeutic agent indicated for colorectal carcinoma, which would not be clinically applicable due to its very poorly soluble and hydrolytic degradation properties. To overcome these limitations, it was proposed to conjugate

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