137723
2,4,6-Triiodophenol
97%
Synonym(s):
Bobel 24
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About This Item
Linear Formula:
I3C6H2OH
CAS Number:
Molecular Weight:
471.80
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
210-186-7
MDL number:
Assay:
97%
Form:
powder
Quality Level
assay
97%
form
powder
mp
157-159 °C (lit.)
functional group
iodo
SMILES string
Oc1c(I)cc(I)cc1I
InChI
1S/C6H3I3O/c7-3-1-4(8)6(10)5(9)2-3/h1-2,10H
InChI key
VAPDZNUFNKUROY-UHFFFAOYSA-N
General description
2,4,6-Triiodophenol is iodinated disinfection byproduct formed during chlorination of sewage effluents. It is a potent thyroid hormone disrupting chemical.
Application
2,4,6-Triiodophenol was used in an in vitro assay to investigate deiodinase activity in human hepatic microsomes.
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signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Tingting Gong et al.
Chemosphere, 163, 359-365 (2016-08-25)
Iodide is widely present in drinking water sources as well as wastewater effluents. Chlorination and chloramination are the most commonly used disinfection methods. During chlorination or chloramination of drinking water/wastewater effluents, iodide may be oxidized to hypoiodous acid, which may
G J Miroy et al.
Proceedings of the National Academy of Sciences of the United States of America, 93(26), 15051-15056 (1996-12-24)
Transthyretin (TTR) amyloid fibril formation is observed systemically in familial amyloid polyneuropathy and senile systemic amyloidosis and appears to be the causative agent in these diseases. Herein, we demonstrate conclusively that thyroxine (10.8 microM) inhibits TTR fibril formation efficiently in
L García-Capdevila et al.
Journal of chromatography. B, Biomedical sciences and applications, 708(1-2), 169-175 (1998-07-08)
A rapid and simple HPLC method is described for the determination of Bobel-24 (2,4,6-triiodophenol) and other iodinated derivatives in biological samples. The sample preparation was liquid-liquid extraction before injection onto the HPLC system. 2,6-Diiodo-4-methylphenol was used as internal standard. Separation
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 137723-25G | 04061832278506 |