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138045

L-Tyrosine hydrazide

Name: <SC>L</SC>-Tyrosine hydrazide
Brand: ALDRICH

98%, suitable for bioconjugation

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About This Item

Linear Formula:

4-(HO)C₆H₄CH₂CH(NH₂)CONHNH₂

CAS Number:

7662-51-3

Molecular Weight:

195.22

NACRES:

NA.22

PubChem Substance ID:

24848230

UNSPSC Code:

12352209

EC Number:

231-631-1

MDL number:

MFCD00007609

Beilstein/REAXYS Number:

2808635

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Properties

Product Name

L-Tyrosine hydrazide, 98%

assay

98%

form

powder

optical activity

[α]20/D +76°, c = 4.2 in 1 M HCl

reaction suitability

reaction type: solution phase peptide synthesis

technique(s)

bioconjugation: suitable

color

white to faint tan

mp

196-198 °C (lit.)

application(s)

peptide synthesis

SMILES string

NNC(=O)[C@@H](N)Cc1ccc(O)cc1

InChI

1S/C9H13N3O2/c10-8(9(14)12-11)5-6-1-3-7(13)4-2-6/h1-4,8,13H,5,10-11H2,(H,12,14)/t8-/m0/s1

InChI key

MWIXENPCUPDSOS-QMMMGPOBSA-N

Description

Application

Excellent reagent for the resolution of amino acids.

pictograms

GHS07

signalword

Warning

hcodes

H317,H319

pcodes

P261 - P264 - P272 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

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Design and evaluation of hydroxamate derivatives as metal-mediated inhibitors of a protein tyrosine kinase.

Xianfeng Gu et al.

Journal of medicinal chemistry, 49(25), 7532-7539 (2006-12-08)

Protein tyrosine kinases use two Mg(2+) ions as cofactors in catalysis, one as the ATP-Mg complex (M1) and the other as an essential activator (M2). The M2-binding site has high affinity for transition metal cations such as cobalt and zinc.

Global Trade Item Number

SKU	GTIN
138045-5G	04061838732200