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Merck
CN

138045

L-Tyrosine hydrazide

98%, suitable for bioconjugation

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About This Item

Linear Formula:
4-(HO)C6H4CH2CH(NH2)CONHNH2
CAS Number:
7662-51-3
Molecular Weight:
195.22
NACRES:
NA.22
PubChem Substance ID:
24848230
UNSPSC Code:
12352209
EC Number:
231-631-1
MDL number:
MFCD00007609
Beilstein/REAXYS Number:
2808635

Key Documents

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Product Name

L-Tyrosine hydrazide, 98%

InChI key

MWIXENPCUPDSOS-QMMMGPOBSA-N

InChI

1S/C9H13N3O2/c10-8(9(14)12-11)5-6-1-3-7(13)4-2-6/h1-4,8,13H,5,10-11H2,(H,12,14)/t8-/m0/s1

SMILES string

NNC(=O)[C@@H](N)Cc1ccc(O)cc1

assay

98%

form

powder

optical activity

[α]20/D +76°, c = 4.2 in 1 M HCl

reaction suitability

reaction type: solution phase peptide synthesis

technique(s)

bioconjugation: suitable

color

white to faint tan

mp

196-198 °C (lit.)

application(s)

peptide synthesis

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Application

Excellent reagent for the resolution of amino acids.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317,H319

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
1451757V
1451755V
1451755
1451757
048200/1

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Xianfeng Gu et al.
Journal of medicinal chemistry, 49(25), 7532-7539 (2006-12-08)
Protein tyrosine kinases use two Mg(2+) ions as cofactors in catalysis, one as the ATP-Mg complex (M1) and the other as an essential activator (M2). The M2-binding site has high affinity for transition metal cations such as cobalt and zinc.

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