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Merck
CN

13900

O-Benzyl-L-serine

≥99.0% (NT)

Synonym(s):

(S)-2-Amino-3-benzyloxypropionic acid

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About This Item

Empirical Formula (Hill Notation):
C10H13NO3
CAS Number:
Molecular Weight:
195.22
UNSPSC Code:
12352200
NACRES:
NA.22
PubChem Substance ID:
EC Number:
225-220-6
Beilstein/REAXYS Number:
2114846
MDL number:
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assay

≥99.0% (NT)

form

powder

optical activity

[α]20/D +21±2°, c = 2% in acetic acid: water (4:1) (+ 1 Eq HCl)

optical purity

enantiomeric ratio: ≥99.5:0.5 (TLC)

reaction suitability

reaction type: solution phase peptide synthesis

mp

~227 °C (dec.)

application(s)

peptide synthesis

SMILES string

N[C@@H](COCc1ccccc1)C(O)=O

InChI

1S/C10H13NO3/c11-9(10(12)13)7-14-6-8-4-2-1-3-5-8/h1-5,9H,6-7,11H2,(H,12,13)/t9-/m0/s1

InChI key

IDGQXGPQOGUGIX-VIFPVBQESA-N



Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Amir H Ghassemi et al.
Pharmaceutical research, 27(9), 2008-2017 (2010-07-06)
To study the release of a model protein, bovine serum albumin (BSA), from microspheres of an hydroxylated aliphatic polyester, poly(lactic-co-hydroxymethyl glycolic acid) (PLHMGA). BSA-loaded microspheres were prepared by a double emulsion solvent evaporation method. The effect of copolymer composition and
Amir H Ghassemi et al.
Pharmaceutical research, 29(1), 110-120 (2011-07-12)
To investigate the in vitro release of octreotide acetate, a somatostatin agonist, from microspheres based on a hydrophilic polyester, poly(D,L-lactide-co-hydroxymethyl glycolide) (PLHMGA). Spherical and non-porous octreotide-loaded PLHMGA microspheres (12 to 16 μm) and loading efficiency of 60-70% were prepared by a
Roman V Uzhachenko et al.
Cell reports, 35(1), 108944-108944 (2021-04-08)
Inhibitors of cyclin-dependent kinases 4 and 6 (CDK4/6i) delay progression of metastatic breast cancer. However, complete responses are uncommon and tumors eventually relapse. Here, we show that CDK4/6i can enhance efficacy of T cell-based therapies, such as adoptive T cell transfer or



Global Trade Item Number

SKUGTIN
13900-5G-F04061832641072