139114
(−)-Borneol
predominantly endo, 97%
Synonym(s):
endo-(1S)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol
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About This Item
Empirical Formula (Hill Notation):
C10H18O
CAS Number:
Molecular Weight:
154.25
UNSPSC Code:
12352212
NACRES:
NA.22
PubChem Substance ID:
EC Number:
207-353-1
Beilstein/REAXYS Number:
2038053
MDL number:
Assay:
97%
Form:
solid
vapor density
5.31 (vs air)
Quality Level
vapor pressure
33.5 mmHg ( 25 °C)
assay
97%
form
solid
optical activity
[α]20/D −35.3°, c = 5 in ethanol
bp
210 °C (lit.)
mp
206-208 °C (lit.)
functional group
hydroxyl
SMILES string
[H][C@]12CC[C@](C)([C@H](O)C1)C2(C)C
InChI
1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3/t7-,8+,10+/m0/s1
InChI key
DTGKSKDOIYIVQL-QXFUBDJGSA-N
General description
(-)-Borneol is a bicyclic monoterpene found in essential oils.
Application
(-)-Borneol has been used to study its antiapoptotic, antioxidative and neuroprotective effect in human neuroblastoma cells (SH-SY5Y).
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signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 3 - Flam. Sol. 2 - Skin Sens. 1
Storage Class
4.1B - Flammable solid hazardous materials
wgk
WGK 2
flash_point_f
150.8 °F
flash_point_c
66 °C
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Regulatory Information
危险化学品
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(+)-And (-)-borneol: efficacious positive modulators of GABA action at human recombinant a 1 ? 2 ? 2L GABA A receptors.
Granger RE, et al.
Biochemical Pharmacology, 69(7), 1101-1111 (2005)
Jing-yi Zhao et al.
Journal of Zhejiang University. Science. B, 13(12), 990-996 (2012-12-12)
Borneol, a monoterpenoid alcohol, is used widely, particularly in combined formulas for preventing and curing cardiovascular and cerebrovascular diseases in traditional Chinese medicine. In order to understand the blood and brain pharmacokinetics after intravenous, intranasal, or oral administration and to
Xiao-Hong Wei et al.
Microcirculation (New York, N.Y. : 1994), 20(1), 17-29 (2012-08-24)
The present study was designed to evaluate whether CP was beneficial in alleviating myocardial fibrosis following I/R injury. Sprague-Dawley rats were subjected to 30 minutes occlusion of the LADCA, followed by reperfusion. CP (0.4 or 0.8 g/kg) was daily administered starting from
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 139114-500G | 04061833037799 |
| 139114-100G | 04061838732651 |