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Merck
CN

139114

(−)-右旋龙脑

predominantly endo, 97%

别名:

-(1S)-1,7,7-三甲基二环[2.2.1]庚-2-醇

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关于此项目

经验公式(希尔记法):
C10H18O
化学文摘社编号:
分子量:
154.25
UNSPSC Code:
12352212
NACRES:
NA.22
PubChem Substance ID:
EC Number:
207-353-1
Beilstein/REAXYS Number:
2038053
MDL number:
Assay:
97%
Form:
solid
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产品名称

(−)-右旋龙脑, predominantly endo, 97%

assay

97%

form

solid

InChI key

DTGKSKDOIYIVQL-QXFUBDJGSA-N

InChI

1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3/t7-,8+,10+/m0/s1

SMILES string

[H][C@]12CC[C@](C)([C@H](O)C1)C2(C)C

vapor density

5.31 (vs air)

vapor pressure

33.5 mmHg ( 25 °C)

optical activity

[α]20/D −35.3°, c = 5 in ethanol

bp

210 °C (lit.)

mp

206-208 °C (lit.)

functional group

hydroxyl

Quality Level

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Application

(-)-冰片已被用于研究其在人神经母细胞瘤细胞(SH-SY5Y)中的抗细胞凋亡、抗氧化和神经保护作用。

General description

(-)-冰片是一种在精油中发现的双环单萜烯。

pictograms

FlameExclamation mark

signalword

Warning

Hazard Classifications

Aquatic Chronic 3 - Flam. Sol. 2 - Skin Sens. 1

存储类别

4.1B - Flammable solid hazardous materials

wgk

WGK 2

flash_point_f

150.8 °F

flash_point_c

66 °C

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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(+)-And (-)-borneol: efficacious positive modulators of GABA action at human recombinant a 1 ? 2 ? 2L GABA A receptors.
Granger RE, et al.
Biochemical Pharmacology, 69(7), 1101-1111 (2005)
Jinyoung Hur et al.
Pharmaceutical biology, 51(1), 30-35 (2012-11-09)
The β-amyloid (Aβ) peptide aggregation with accompanying oxidative stress plays the major role in the pathogenesis of Alzheimer's disease (AD). Some natural compounds, including borneol, shed promising light on AD treatment. The present study was designed to investigate the antioxidative
Eva Horváthová et al.
Mutagenesis, 27(5), 581-588 (2012-05-01)
Experimental evidences suggest that most essential oils possess a wide range of biological and pharmacological activities that may protect tissues against oxidative damage. In this study, we investigated DNA-protective effect of borneol, a component of many essential oils, against oxidative
Zhen-Yu Xiong et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(6), 786-790 (2013-05-31)
Borneol is a major component of many medicinal plant essential oils, as well as a popular traditional Chinese medicine. This essay collects the results of the latest domestic and foreign studies, and summarizes and analyzes its activity and reaction mechanism
Xiao Song et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(18), 2489-2492 (2012-01-20)
To investigate the absorption characteristic of borneol. Using single pass perfusion model, the active ingredient of borneol were detected by GC. The drug concentration, perfusion rate and pH value on the absorption of borneol were studied. Perfusion rate on the

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