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Merck
CN

14050

Berberine chloride hydrate

technical, ≥90% (AT)

Synonym(s):

Natural Yellow 18

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About This Item

Empirical Formula (Hill Notation):
C20H18ClNO4 · xH2O
CAS Number:
Molecular Weight:
371.81 (anhydrous basis)
UNSPSC Code:
12352103
NACRES:
NA.22
PubChem Substance ID:
EC Number:
211-195-9
Colour Index Number:
75160
MDL number:
Assay:
≥90% (AT)
Form:
powder
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Quality Level

grade

technical

assay

≥90% (AT)

form

powder

mp

204-206 °C (dec.)

SMILES string

[Cl-].COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OC

InChI

1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1

InChI key

VKJGBAJNNALVAV-UHFFFAOYSA-M



Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Lamyae El Khalki et al.
Molecules (Basel, Switzerland), 25(3) (2020-01-30)
Triple negative breast cancer (TNBC) is an aggressive breast cancer subtype. Non-available targeted therapy for TNBC represents its biggest treatment challenge. Thus, finding new promising effective drugs is urgently needed. In the present study, we investigated how berberine, a natural
Sayan Biswas et al.
Pharmaceutical development and technology, 26(1), 69-80 (2020-10-17)
Piper species is one of the most widely consumed spices for culinary purposes. Piperine (PIP) present in Piper species has a wide range of therapeutic activity including hepatoprotection. However, the major biological limitation of PIP is its low bioavailability after
Cemile Selin Aksoy et al.
Microbial pathogenesis, 149, 104542-104542 (2020-10-04)
A plethora of natural products emerges as attractive molecules in the struggle against antibiotic resistance. These molecules impose their bioactivities not only alone but also in combinations as well, which further enhances their effects. Berberine is a well-known isoquinoline alkaloid



Global Trade Item Number

SKUGTIN
14050-50G04061838733474
14050-10G04061838733467