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Merck
CN

141879

(−)-Lobeline hydrochloride

98%

Synonym(s):

α-Lobeline hydrochloride, L-Lobeline hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C22H27NO2 · HCl
CAS Number:
Molecular Weight:
373.92
UNSPSC Code:
12352005
NACRES:
NA.22
PubChem Substance ID:
EC Number:
205-150-2
Beilstein/REAXYS Number:
3920196
MDL number:
Assay:
98%
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Quality Level

assay

98%

optical activity

[α]20/D −56.8°, c = 2 in H2O

mp

183-185 °C (dec.) (lit.)

functional group

hydroxyl, ketone, phenyl

SMILES string

Cl[H].CN1[C@@H](CCC[C@@H]1CC(=O)c2ccccc2)C[C@H](O)c3ccccc3

InChI

1S/C22H27NO2.ClH/c1-23-19(15-21(24)17-9-4-2-5-10-17)13-8-14-20(23)16-22(25)18-11-6-3-7-12-18;/h2-7,9-12,19-21,24H,8,13-16H2,1H3;1H/t19-,20+,21-;/m0./s1

InChI key

MKMYPTLXLWOUSO-NFQNBQCWSA-N



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Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

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Jeong-Ho Park et al.
FEBS letters, 590(4), 493-500 (2016-01-24)
The intestine is involved in digestion and absorption, as well as the regulation of metabolism upon sensation of the internal intestinal environment. Enteroendocrine cells are thought to mediate these internal intestinal chemosensory functions. Using the CaLexA (calcium-dependent nuclear import of
Hany Km Dweck et al.
eLife, 10 (2021-02-23)
Although most Drosophila species lay eggs in overripe fruit, the agricultural pest Drosophila suzukii lays eggs in ripe fruit. We found that changes in bitter taste perception have accompanied this adaptation. We show that bitter-sensing mutants of Drosophila melanogaster undergo
Jaekyun Choi et al.
eNeuro, 7(2) (2020-03-30)
Feeding, a critical behavior for survival, consists of a complex series of behavioral steps. In Drosophila larvae, the initial steps of feeding are food choice, during which the quality of a potential food source is judged, and ingestion, during which



Global Trade Item Number

SKUGTIN
141879-1G04061838734198