143073
Diglycolic acid
98%
Synonym(s):
2,2′-Oxydiacetic acid
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About This Item
Linear Formula:
O(CH2COOH)2
CAS Number:
Molecular Weight:
134.09
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
203-823-5
Beilstein/REAXYS Number:
1072117
MDL number:
Assay:
98%
Quality Level
assay
98%
mp
140-144 °C (lit.)
solubility
ethanol: soluble 5%, clear to slightly hazy, colorless to greenish-yellow
functional group
carboxylic acid, ether
SMILES string
OC(=O)COCC(O)=O
InChI
1S/C4H6O5/c5-3(6)1-9-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)
InChI key
QEVGZEDELICMKH-UHFFFAOYSA-N
General description
Diglycolic acid is a toxic metabolite of diethylene glycol (DEG) responsible for DEG-induced proximal tubular necrosis.
Application
Diglycolic acid was used in the preparation of needle-like aragonite particles from calcium nitrate aqueous solutions.
Biochem/physiol Actions
Diglycolic acid has antithrombogenic properties and induces vasodilation. It inhibits succinate dehydrogenase activity in human proximal tubule cells.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Zahraa Youssef et al.
Photodiagnosis and photodynamic therapy, 22, 115-126 (2018-03-28)
In this study, light-sensitive photosensitizers (Chlorin e6, Ce6) were linked to TiO2 and SiO2 nanoparticles (NPs) in order to develop new kinds of NP-based drug delivery systems for cancer treatment by PDT. TiO2 or SiO2 NPs were modified either by
Miriam E Mossoba et al.
Toxicology in vitro : an international journal published in association with BIBRA, 52, 87-93 (2018-06-12)
Carboxymethyl starches are added to food products for thickening or tablet binding/filling purposes. Although they lack toxicity, their synthesis creates the chemical byproduct diglycolic acid (DGA), which is difficult to eliminate and whose toxicity is in question. A rare case
Preparation of needle-like aragonite particles from calcium nitrate solution.
Fellner P, et al.
Acta Chimica Slovenica, 4(2), 3-10 (2011)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 143073-5G | 04061838734686 |
| 143073-1KG | 04061838734679 |
| 143073-100G | 04061838734662 |