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14501

Poly(ethylene glycol) bis(amine)

Name: Poly(ethylene glycol) bis(amine)
Brand: ALDRICH

Mw 2,000, carboxyl reactive, amine

Synonym(s):

Polyethylene glycol, O,O′-Bis(2-aminoethyl)polyethylene glycol, Diaminopolyethylene glycol, PEG-diamine, Polyoxyethylene bis(amine)

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About This Item

Linear Formula:

H₂N(CH₂CH₂O)_nCH₂CH₂NH₂

CAS Number:

24991-53-5

UNSPSC Code:

12162002

PubChem Substance ID:

24848541

NACRES:

NA.23

MDL number:

MFCD00132004

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Properties

Product Name

Poly(ethylene glycol) bis(amine), M_w 2,000

form

powder

Quality Level

100

mol wt

M_w 2,000

reaction suitability

reagent type: cross-linking reagent
reactivity: carboxyl reactive

Ω-end

amine

α-end

amine

polymer architecture

shape: linear
functionality: homobifunctional

storage temp.

−20°C

SMILES string

NCCOCCOCCN

InChI

1S/C6H16N2O2/c7-1-3-9-5-6-10-4-2-8/h1-8H2

InChI key

IWBOPFCKHIJFMS-UHFFFAOYSA-N

Description

Application

Polyethylene Glycol Conjugated Polymeric Nanocapsules for Targeted Delivery of Quercetin to Folate-Expressing Cancer Cells in Vitro and in Vivo: Discusses the use of PEG-bis amine for creating polymeric nanocapsules aimed at enhancing targeted drug delivery (RI El-Gogary et al., 2014).

Other Notes

Polymer for preparing enzyme conjugates soluble in organic solvents; Promising drug carrier

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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

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Articles

Versatile Cell Culture Scaffolds: Bio-orthogonal Click

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Direct writing of optical microresonators in a lab-on-a-chip for label-free biosensing.

L Kelemen et al.

Lab on a chip, 19(11), 1985-1990 (2019-05-03)

Whispering gallery mode (WGM) resonators are promising optical structures for microfluidic label-free biosensors mainly due to their high sensitivity, but from a practical point of view they present numerous constraints that make their use in real laboratory diagnosis application difficult.

Amino acids and peptides. XXV. Preparation of fibronectin-related peptide poly(ethylene glycol) hybrids and their inhibitory effect on experimental metastasis.

K Kawasaki et al.

Chemical & pharmaceutical bulletin, 43(12), 2133-2138 (1995-12-01)

Hybrids of fibronectin-related peptides [Arg-Gly-Asp (RGD), Arg-Gly-Asp-Ser (RGDS)] and poly(ethylene glycol) (PEG) were prepared and their inhibitory effects on experimental metastasis in mice were examined. The inhibitory effect of RGD was markedly potentiated by hybrid formation with poly(ethylene glycol) #6000.

Urrotigoity, M. and Souppe, J.

Biocatalysis, 2, 145-145 (1989)

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Global Trade Item Number

SKU	GTIN
394920-1ML	04061837809347
394920-10X1ML	04061837810961
346128-10G	04061838126719
346128-1G	04061838135391
394920-5ML	04061837810978
14501-250MG	04061833278727
14501-1G	04061838736062