154334
2,5-Diaminotoluene sulfate
97%
Synonym(s):
2-Methyl-p-phenylenediamine sulfate salt, 2,5-Toluenediamine sulfate
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About This Item
Linear Formula:
CH3C6H3(NH2)2 · H2SO4
CAS Number:
Molecular Weight:
220.25
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
210-431-8
Beilstein/REAXYS Number:
3755478
MDL number:
assay
97%
mp
>300 °C (lit.)
SMILES string
OS(O)(=O)=O.Cc1cc(N)ccc1N
InChI
1S/C7H10N2.H2O4S/c1-5-4-6(8)2-3-7(5)9;1-5(2,3)4/h2-4H,8-9H2,1H3;(H2,1,2,3,4)
InChI key
KZTWOUOZKZQDMN-UHFFFAOYSA-N
General description
2,5-Diaminotoluene sulfate occurs as an intermediate during hair dye formulation.
signalword
Danger
Hazard Classifications
Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 2 - Skin Sens. 1
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Regulatory Information
危险化学品
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Long-term toxicity studies on oxidation hair dyes.
C Burnett et al.
Food and cosmetics toxicology, 13(3), 353-357 (1975-06-01)
Andrew Scheman et al.
Dermatitis : contact, atopic, occupational, drug, 22(4), 189-192 (2011-07-26)
Finding alternative hair dyes for individuals allergic to para-phenylenediamine (PPD) has been difficult. Newer permanent and demipermanent hair dyes that have replaced PPD with para-toluenediamine sulfate (PTDS) are now available. We examined whether individuals allergic to PPD will tolerate PPD-free
Severe aplastic anaemia following the use of hair dye: report of two cases and review of literature.
J E Hopkins et al.
Postgraduate medical journal, 61(721), 1003-1005 (1985-11-01)
We describe two female patients aged 31 and 62 y who developed severe aplastic anaemia following the use of hair dye containing para-toluenediamine. One received a bone marrow transplant but died after developing graft versus host disease and severe opportunistic