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Sigma-Aldrich

4-(Benzyloxy)phenol

98%

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Synonym(s):
4-(Phenylmethoxy)phenol, Hydroquinone monobenzyl ether
Linear Formula:
C6H5CH2OC6H4OH
CAS Number:
103-16-2
Molecular Weight:
200.23
Beilstein:
1958305
EC Number:
203-083-3
MDL number:
MFCD00002333
PubChem Substance ID:
24849729
NACRES:
NA.22

Quality Level

100

Assay

98%

form

solid

mp

119-120 °C (lit.)

SMILES string

Oc1ccc(OCc2ccccc2)cc1

InChI

1S/C13H12O2/c14-12-6-8-13(9-7-12)15-10-11-4-2-1-3-5-11/h1-9,14H,10H2

InChI key

VYQNWZOUAUKGHI-UHFFFAOYSA-N

Gene Information

human ... TYR(7299)
rat ... Ar(24208)

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Application

4-(Benzyloxy)phenol was used in the synthesis of bis(4-benzyloxyphenoxy)phenyl phosphine oxide. It was also used in the preparation of series of hetaryl-azophenol dyes via heterocyclic amines in nitrosyl sulphuric acid.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317 - H319

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Synthesis, spectral properties, biological activity and application of new 4-(benzyloxy) phenol derived azo dyes for polyester fiber dyeing.
Yousefi H, et al.
Journal of Molecular Liquids, 180, 51-58 (2013)
Behrooz Kasraee et al.
Experimental dermatology, 15(7), 509-514 (2006-06-10)
Monobenzylether of hydroquinone (MBEH) has long been utilized for the depigmentation therapy of patients with extensive vitiligo. In this approach, the normally pigmented areas surrounding vitiligo lesions are depigmented to achieve a uniform skin tone. One of the important disadvantages
Synthesis, characterization and thermal degradation of functional benzoxazine monomers and polymers containing phenylphosphine oxide.
Choi S-W, et al.
Polymer Degradation and Stability, 91(5), 1166-1178 (2006)
M D Njoo et al.
Archives of dermatology, 135(12), 1514-1521 (1999-12-22)
To develop and introduce evidence-based guidelines for the treatment of vitiligo in children and in adults. Patients, residents, and dermatologists from the Department of Dermatology, Academic Medical Center, University of Amsterdam, and the Netherlands Institute for Pigmentary Disorders in Amsterdam.
Jasper G van den Boorn et al.
PloS one, 5(5), e10626-e10626 (2010-05-26)
Presently melanoma still lacks adequate treatment options for metastatic disease. While melanoma is exceptionally challenging to standard regimens, it is suited for treatment with immunotherapy based on its immunogenicity. Since treatment-related skin depigmentation is considered a favourable prognostic sign during
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