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Merck
CN

160415

3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine

≥99%

Synonym(s):

5,6-Diphenyl-3-(2-pyridyl)-1,2,4-triazine, PDT

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About This Item

Empirical Formula (Hill Notation):
C20H14N4
CAS Number:
1046-56-6
Molecular Weight:
310.35
Beilstein:
542151
EC Number:
213-878-7
MDL number:
MFCD00006462
UNSPSC Code:
12352100
PubChem Substance ID:
24849870
NACRES:
NA.22

Key Documents

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Assay

≥99%

mp

191-193 °C (lit.)

functional group

phenyl

SMILES string

c1ccc(cc1)-c2nnc(nc2-c3ccccc3)-c4ccccn4

InChI

1S/C20H14N4/c1-3-9-15(10-4-1)18-19(16-11-5-2-6-12-16)23-24-20(22-18)17-13-7-8-14-21-17/h1-14H

InChI key

OTMYLOBWDNFTLO-UHFFFAOYSA-N

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General description

3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine (PDT) reacts with Cu(II) perchlorate in ethanol to yield [Cu(PDT)2(ClO4)2].

Application

3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine was employed as chromogenic-extraction reagent during spectrophotometric determination of iron in acids and acidic solutions. It was also employed as precolumn derivatizing reagent in the HPLC method with UV absorbance detection for the Fe(II) determination.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF6138V
WXBF2048V
WXBF0785V
WXBD8081V
WXBD9076V

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Sungsoon Hwang et al.
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To report the clinical outcomes of reduced-fluence photodynamic therapy (PDT) for symptomatic subfoveal retinal pigment epithelial detachment (RPED) in central serous chorioretinopathy and identify prognostic factors affecting treatment outcome. This retrospective interventional study included 35 eyes of 35 patients with
Yvonne H W Derks et al.
Theranostics, 11(4), 1527-1541 (2021-01-08)
Incomplete resection of prostate cancer (PCa) occurs in 15%-50% of PCa patients. Disease recurrence negatively impacts oncological outcome. The use of radio-, fluorescent-, or photosensitizer-labeled ligands to target the prostate-specific membrane antigen (PSMA) has become a well-established method for the
Yu-Cherng Channing Chang et al.
Scientific reports, 7(1), 9746-9746 (2017-08-31)
Tumor heterogeneity can be elucidated by mapping subregions of the lesion with differential imaging characteristics, called habitats. Dynamic Contrast Enhanced (DCE-)MRI can depict the tumor microenvironments by identifying areas with variable perfusion and vascular permeability, since individual tumor habitats vary
Thomas J van Rijssen et al.
PloS one, 13(8), e0202549-e0202549 (2018-08-25)
To assess parameters on optical coherence tomography (OCT), and their correlation with best-corrected visual acuity (BCVA) in patients with non-resolving central serous chorioretinopathy (CSC). For 25 non-resolving CSC patients treated with photodynamic therapy (PDT), the thickness of retinal layers was
Nikolay Polyakov et al.
Antioxidants & redox signaling, 28(15), 1394-1403 (2017-11-23)
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