162973
2-[2-(2-Chloroethoxy)ethoxy]ethanol
96%
Synonym(s):
Triethylene glycol monochlorohydrin
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About This Item
Linear Formula:
Cl(CH2CH2O)2CH2CH2OH
CAS Number:
Molecular Weight:
168.62
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
225-984-0
Beilstein/REAXYS Number:
1739194
MDL number:
Assay:
96%
Form:
liquid
InChI key
KECMLGZOQMJIBM-UHFFFAOYSA-N
InChI
1S/C6H13ClO3/c7-1-3-9-5-6-10-4-2-8/h8H,1-6H2
SMILES string
OCCOCCOCCCl
assay
96%
form
liquid
refractive index
n20/D 1.458 (lit.)
bp
117-120 °C/5 mmHg (lit.)
density
1.16 g/mL at 25 °C (lit.)
Quality Level
Related Categories
Application
2-[2-(2-Chloroethoxy)ethoxy]ethanol was used in the synthesis of 1-[3-(2-aminoethyl)-1H-indol-5-yloxy]-3,6-dioxa-8-mercaptooctane. It was also used in the synthesis of modified oligonucleotides bearing a disulfide or a thiol function at the 3′-end and other modifications at the 5′-end.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
224.6 °F - closed cup
flash_point_c
107 °C - closed cup
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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Solid phase synthesis of 5', 3'-bifunctional oligodeoxyribonucleotides bearing a masked thiol group at the 3'-end.
Bonfils E and Thuong NT.
Tetrahedron Letters, 32(26), 3053-3056 (1991)
Sandra J Rosenthal et al.
Journal of the American Chemical Society, 124(17), 4586-4594 (2002-04-25)
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Po-Chih Yang et al.
Polymers, 11(12) (2019-12-11)
This paper gathered studies on multistimulus-responsive sensing and self-assembly behavior of a novel amphiphilic diblock copolymer through a two-step reverse addition-fragmentation transfer (RAFT) polymerization technique. N-Isopropylacrylamide (NIPAM) macromolecular chain transfer agent and diblock copolymer (poly(NIPAM-b-Azo)) were discovered to have moderate
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