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170925

Sigma-Aldrich

4-Nitrobenzenesulfonyl chloride

technical grade, 90%

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Linear Formula:
O2NC6H4SO2Cl
CAS Number:
Molecular Weight:
221.62
Beilstein:
746543
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

grade

technical grade

Quality Level

Assay

90%

mp

66-70 °C (lit.)

SMILES string

[O-][N+](=O)c1ccc(cc1)S(Cl)(=O)=O

InChI

1S/C6H4ClNO4S/c7-13(11,12)6-3-1-5(2-4-6)8(9)10/h1-4H

InChI key

JXRGUPLJCCDGKG-UHFFFAOYSA-N

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Application

4-Nitrobenzenesulfonyl chloride was used in the synthesis of [Cu(bipy)2Cl](nbs) where bipy = 2,2′-bipyridine, nbs = 4-nitrobenzenesulfonate. It was also used to determine estrogens in biological fluids.

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Repr. 2 - Skin Sens. 1A

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Tatsuya Higashi et al.
Analytical and bioanalytical chemistry, 386(3), 658-665 (2006-04-13)
A practical procedure for determining estrogens in biological fluids has been studied using liquid chromatography-electron capture atmospheric pressure chemical ionization-mass spectrometry combined with derivatization. Among the commercially available reagents (4-nitrobenzoyl chloride, 2,4-dinitrofluorobenzene, 4-nitrobenzenesulfonyl chloride and 4-nitrobenzyl bromide), 4-nitrobenzenesulfonyl chloride was
Mahboubeh A Sharif et al.
Acta chimica Slovenica, 59(2), 289-293 (2012-06-01)
[Cu(bipy)2Cl](nbs) (1) (bipy = 2,2'-bipyridine, nbs = 4-nitrobenzenesulfonate) was obtained from the reaction of 4-nitrobenzenesulfonyl chloride and 2-amine-4-methylopyridine with CuCl2 in the presence of 2,2'-bipyridine and characterized by elemental analysis, IR spectra and X-ray single-crystal diffraction. The asymmetric unit of
Tsurng-Juhn Huang et al.
European journal of medicinal chemistry, 90, 428-435 (2014-12-03)
Hepatitis B virus (HBV) is a causative reagent that frequently causes progressive liver diseases, leading to the development of acute, chronic hepatitis, cirrhosis, and eventually hepatocellular carcinoma (HCC). Despite several antiviral drugs including interferon-α and nucleotide derivatives are approved for

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