180386
2,2,2-Trifluoroethylamine hydrochloride
98%
Synonym(s):
2-Amino-1,1,1-trifluoroethane hydrochloride
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About This Item
Linear Formula:
CF3CH2NH2 · HCl
CAS Number:
Molecular Weight:
135.52
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
206-771-1
Beilstein/REAXYS Number:
3652103
MDL number:
Assay:
98%
InChI key
ZTUJDPKOHPKRMO-UHFFFAOYSA-N
InChI
1S/C2H4F3N.ClH/c3-2(4,5)1-6;/h1,6H2;1H
SMILES string
Cl.NCC(F)(F)F
assay
98%
mp
220-222 °C (subl.) (lit.)
functional group
amine, fluoro
Quality Level
Related Categories
Application
2,2,2-Trifluoroethylamine hydrochloride was used in the derivatization of aqueous carboxylic acids to the corresponding 2,2,2-trifluoroethylamide derivative.
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Warning
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
hcodes
Hazard Classifications
Acute Tox. 4 Oral
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Quincy LaRon Ford et al.
Journal of chromatography. A, 1145(1-2), 241-245 (2007-02-20)
We report a technique for the rapid, room temperature derivatization of aqueous carboxylic acids to the corresponding 2,2,2-trifluoroethylamide derivative. 3-Ethyl-1-[3-(dimethylamino)propyl]carbodiimide hydrochloride (EDC) and 2,2,2-trifluoroethylamine hydrochloride (TFEA) were added to aqueous samples of several acids of interest in environmental analytical chemistry
Yoshikazu Hattori et al.
Journal of biomolecular NMR, 68(4), 271-279 (2017-08-02)
The preparation of stable isotope-labeled proteins is important for NMR studies, however, it is often hampered in the case of eukaryotic proteins which are not readily expressed in Escherichia coli. Such proteins are often conveniently investigated following post-expression chemical isotope
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