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181609

Sigma-Aldrich

Polycaprolactone

average Mw ~65,000, average Mn ~42,500, pellets

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Synonym(s):
2-Oxepanone homopolymer, 6-Caprolactone polymer
Linear Formula:
(C6H10O2)n

form

pellets

melt index

1.9 g/10 min (80°C/0.3 Mpa)

mol wt

average Mn ~42,500
average Mw ~65,000

impact strength

82 J/m (Izod, ASTM D 256-73A, notched)

hardness

55 (Shore D, ASTM D 2240-75)

mp

60 °C (lit.)

elongation

2 in/min - 600-1000% (ultimate)

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Application

Extrusion aid, die lubricant, mold release, pigment and filler dispersion aid and polyester segments in urethanes and block polyesters.

Features and Benefits

Biodegradable polymer
Non-toxic, biodegradable in soil, broad miscibility, mechanical compatibility with many polymers and good adhesion to a broad spectrum of substrates.

Regulatory Information

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Richard A Thibault et al.
Journal of biomedical materials research. Part A, 101(5), 1225-1236 (2013-03-19)
Devitalization and demineralization processing of biodegradable polymer and extracellular matrix (ECM) hybrid constructs was explored for the effect on the retention of ECM components and construct osteogenicity. Hybrid constructs were generated by seeding osteogenically predifferentiated rat mesenchymal stem cells (MSCs)
Jing Bao et al.
Journal of biomedical nanotechnology, 9(7), 1173-1180 (2013-08-06)
In this study, a berberine-loaded electrospun poly-(epsilon-caprolactone) nanofibrous membrane (B-NFM) was formulated. The B-NFM was composed of uniform nanofibers with the average diameter of 190 +/- 53 nm. Whole blood assay revealed that the B-NFM had higher absorption capacity than
Adriana Raffin Pohlmann et al.
Expert opinion on drug delivery, 10(5), 623-638 (2013-02-08)
Poly(ϵ-caprolactone) (PCL), a biodegradable and biocompatible polymer, is useful to encapsulate a wide range of drugs making it an interesting material for the preparation of carriers with potential applications in therapeutics. The design and development of those carriers to modulate
Y C Chien et al.
Environmental technology, 34(1-4), 149-155 (2013-03-28)
Polycaprolactone (PCL) is one of the most attractive biodegradable plastics that has been widely used in medicine and agriculture fields. Because of the large increase in biodegradable plastics usage, the production of waste biodegradable plastics will be increasing dramatically, producing
Qingchun Zhang et al.
Materials science & engineering. C, Materials for biological applications, 33(4), 2094-2103 (2013-03-19)
The physical properties of tissue engineering scaffolds such as microstructures play important roles in controlling cellular behaviors and neotissue formation. Among them, the pore size stands out as a key determinant factor. In the present study, we aimed to fabricate
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