191337
1-(4-Fluorophenyl)piperazine
98%
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About This Item
Empirical Formula (Hill Notation):
C10H13FN2
CAS Number:
Molecular Weight:
180.22
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
218-846-6
MDL number:
Assay:
98%
Form:
solid
Quality Level
assay
98%
form
solid
drug control
Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet, kontrollierte Droge in Deutschland
bp
118-123 °C/0.1 mmHg (lit.)
mp
30-33 °C (lit.)
SMILES string
Fc1ccc(cc1)N2CCNCC2
InChI
1S/C10H13FN2/c11-9-1-3-10(4-2-9)13-7-5-12-6-8-13/h1-4,12H,5-8H2
InChI key
AVJKDKWRVSSJPK-UHFFFAOYSA-N
Gene Information
rat ... Chrnb2(54239)
Application
1-(4-Fluorophenyl)piperazine was used in the synthesis of N,N-disubstituted piperazine.
Legal Information
German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.
English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.
English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Craig A Stockmeier et al.
Journal of psychiatric research, 43(10), 887-894 (2009-02-14)
Serotonin-1A receptors may play a role in the pathophysiology of depression and suicide. In postmortem brain tissue, agonist binding to serotonin-1A receptors is reportedly increased or unchanged in depression or suicide, while neuroimaging studies report a decrease in antagonist binding
Rapid synthesis of N, N'-disubstituted piperazines. Application to the preparation of No carrier added 1-(4-[18F] fluorophenyl) piperazine and of an [18F]-selective ligand of serotoninergic receptors (5HT2 antagonist).
Collins M, et al.
Journal of the Chemical Society. Perkin Transactions 1, 23, 3185-3188 (1992)
P E Keane et al.
Neuropharmacology, 21(2), 163-169 (1982-02-01)
Niaprazine (60 mg/kg i.p.) increased rat brain 5-hydroxyindole acetic acid (5-HIAA) concentrations 30 min after treatment, and reduced them at 3-8 hr after treatment. Rat brain 5-hydroxytryptamine (5-HT) levels were unchanged. Niaprazine also produced a short-lasting depletion of rat brain
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 191337-10G | 04061833544952 |