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Merck
CN

191523

3,9-Divinyl-2,4,8,10-tetraoxaspiro[5.5]undecane

98%

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About This Item

Empirical Formula (Hill Notation):
C11H16O4
CAS Number:
Molecular Weight:
212.24
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
201-092-7
MDL number:
Assay:
98%
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assay

98%

bp

108-110 °C/2 mmHg (lit.)

mp

43-46 °C (lit.)

density

1.251 g/mL at 25 °C (lit.)

SMILES string

C=CC1OCC2(CO1)COC(OC2)C=C

InChI

1S/C11H16O4/c1-3-9-12-5-11(6-13-9)7-14-10(4-2)15-8-11/h3-4,9-10H,1-2,5-8H2

InChI key

OOXMQACSWCZQLX-UHFFFAOYSA-N

Application

3,9-Divinyl-2,4,8,10-tetraoxaspiro[5.5]undecane is an acetal-type crosslinking agent comonomer and has been used:
  • in radical emulsion copolymerization of 2-hydroxyethyl methacrylate
  • as cross-linking agent in the synthesis of acid-degradable core-crosslinked micelles
  • in the synthesis of new biocompatible copolymer for loading the indomethacin as drug model


Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)



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Upon the emulsion polymerization of 2-hydroxyethyl methacrylate with 3, 9-divinyl-2, 4, 8, 10-tetraoxaspiro [5.5]-undecane.
Nita LE, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 381(1), 111-117 (2011)
Loredana E Nita et al.
Journal of materials science. Materials in medicine, 23(5), 1211-1223 (2012-03-15)
The study presents the possibility to use the 2-hydroxyethyl methacrylate--HEMA copolymer with a comonomer with spiroacetal moiety, 3,9-divinyl-2,4,8,10-tetraoxaspiro[5.5]-undecane)-U, as polymer network for loading the indomethacin--INN as drug model, and also, the controlled release evaluation of the prepared bioactive system. The
Acid-Degradable Core-Crosslinked Micelles Prepared from Thermosensitive Glycopolymers Synthesized via RAFT Polymerization.
Zhang L, et al.
Macromolecular Rapid Communications, 29(2), 123-129 (2008)



Global Trade Item Number

SKUGTIN
191523-5G04061838760234