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Merck
CN

191906

Hydroxypropyl cellulose

average Mw ~1,000,000, powder, 20 mesh particle size (99% through)

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About This Item

CAS Number:
9004-64-2
UNSPSC Code:
12162002
NACRES:
NA.23
MDL number:
MFCD00132688

Key Documents

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Product Name

Hydroxypropyl cellulose, average Mw ~1,000,000, powder, 20 mesh particle size (99% through)

SMILES string

N(C)(C)c1cc(c(cc1)C(N)CC)C

InChI

1S/C12H20N2/c1-5-12(13)11-7-6-10(14(3)4)8-9(11)2/h6-8,12H,5,13H2,1-4H3

InChI key

RRHXDYJWVYFMKV-UHFFFAOYSA-N

description

biological oxygen demand (BOD) 14,000 ppm

form

powder

autoignition temp.

752 °F

mol wt

average Mw ~1,000,000

impurities

<5 wt. %

particle size

20 mesh (99% through)

pH

5.0-8.5

interfacial tension mineral oil

12.5 dyn/cm, 0.1 wt. % in H2O (vs. mineral oil)

viscosity

1,275-3,500 cP, 1 wt. % in H2O(25 °C, Brookfield, spindle #3) (30 rpm)(lit.)

solubility

H2O: insoluble (above 45 °C)
polar organic solvents: soluble

density

0.5 g/mL at 25 °C (lit.)

Quality Level

100

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Related Categories

Application

  • Thermo-responsive aqueous foams: Hydroxypropyl cellulose has been studied for its properties as a green polymer that can alter its solubility with temperature changes, making it suitable for responsive foam applications (Braunschweig, 2019).
  • Interaction mechanism in aqueous solutions: A study on the interaction between hydroxypropyl cellulose and water in solutions, focusing on the importance of polymer chain length in determining the physical properties of the solutions (Martin-Pastor and Stoyanov, 2020).
  • Corrosion inhibition: Hydroxypropyl cellulose has shown effectiveness as a corrosion inhibitor for aluminium in acidic environments, highlighting its potential in material science and engineering applications (Nwanonenyi et al., 2019).
  • Orally disintegrating films: This application involves the formulation design of hydroxypropyl cellulose films, aiming to enhance the delivery and dissolution profile of pharmaceuticals, making it significant in drug delivery and pharmaceutical sciences (Takeuchi et al., 2018).

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ2521
MKCR8693
MKCN0594
MKCD5599
MKBC6263V

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Catherine Boissier et al.
Journal of pharmaceutical sciences, 101(7), 2512-2522 (2012-04-28)
Nuclear magnetic resonance (NMR) cryoporometry and scanning electron microscopy (SEM) image analysis have been used to investigate the size and shape distribution of pores in pharmaceutical coatings. The coatings were made from a mixture of hydroxypropylcellulose (HPC) and ethylcellulose (EC).
Homendra Naorem et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 101, 67-73 (2012-10-27)
The formation constant of triiodide ions from iodine-iodide equilibrium in aqueous-organic solvent or polymer mixed media have been determined spectrophotometrically at three different temperatures 20, 30 and 40°C. The organic solvents chosen for the study are ethylene glycol, 2-methoxy ethanol
Noorullah Naqvi Mohammed et al.
AAPS PharmSciTech, 13(4), 1158-1169 (2012-09-11)
The objective of this research work was to evaluate Klucel™ hydroxypropylcellulose (HPC) EF and ELF polymers, for solubility enhancement as well as to address some of the disadvantages associated with solid dispersions. Ketoprofen (KPR), a Biopharmaceutics Classification System class II
Kassibla E Dempah et al.
AAPS PharmSciTech, 14(1), 19-28 (2012-11-28)
Solid-state NMR spectroscopy (SSNMR), coupled with powder X-ray diffraction (PXRD), was used to identify the physical forms of gabapentin in samples prepared by recrystallization, spray drying, dehydration, and milling. Four different crystalline forms of gabapentin were observed: form I, a
Ranjit M Dhenge et al.
International journal of pharmaceutics, 438(1-2), 20-32 (2012-09-11)
The present work focuses on the study of the progression of granules in different compartments along the length of screws in a twin screw granulator (TSG). The effects of varying powder feed rate; liquid to solid ratio and viscosity of
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