Skip to Content
Merck
CN

196649

2-Fluorobenzonitrile

98%

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Linear Formula:
FC6H4CN
CAS Number:
394-47-8
Molecular Weight:
121.11
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24851778
EC Number:
206-897-7
Beilstein/REAXYS Number:
2042184
MDL number:
MFCD00001773

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

2-Fluorobenzonitrile, 98%

InChI key

GDHXJNRAJRCGMX-UHFFFAOYSA-N

InChI

1S/C7H4FN/c8-7-4-2-1-3-6(7)5-9/h1-4H

SMILES string

Fc1ccccc1C#N

assay

98%

form

liquid

refractive index

n20/D 1.505 (lit.)

bp

90 °C/21 mmHg (lit.)

density

1.116 g/mL at 25 °C (lit.)

functional group

fluoro
nitrile

Quality Level

200

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

2-Fluorobenzonitrile was used in the synthesis of :
  • 3-amino-1,2-benzisoxazoles
  • 6-(acetylaminomethyl)-3-amino-1,2-benzisoxazole
  • 5-(4′-methyl [1, 1′-biphenyl]-2-yl)-1H-tetrazole
  • xanthone-iminium triflates

General description

2-Fluorobenzonitrile reacts with lithium N,N-dialkylaminoborohydride reagent to yield 2-(N,N-dialkylamino)benzylamines.

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

165.2 °F - closed cup

flash_point_c

74 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCN1609
BCCJ3608
BCCH3491
BCCG4264
BCCB6557

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

H M Colquhoun et al.
Organic letters, 3(15), 2337-2340 (2001-07-21)
[reaction: see text] Condensation of 2-fluorobenzonitriles with phenoxides affords 2-aryloxybenzonitriles that cyclize cleanly in trifluoromethanesulfonic acid at room temperature to give xanthone-iminium triflates. The C=N bond in these compounds is remarkably resistant to hydrolysis, but prolonged reaction with strong aqueous
S Thomas et al.
The Journal of organic chemistry, 66(6), 1999-2004 (2001-04-13)
A novel tandem amination-reduction reaction has been developed in which 2-(N,N-dialkylamino)benzylamines are generated from 2-halobenzonitriles and lithium N,N-dialkylaminoborohydride (LAB) reagents. These reactions are believed to occur through a tandem S(N)Ar amination-reduction mechanism wherein the LAB reagent promotes halide displacement by
Edmund J Norris et al.
PLoS neglected tropical diseases, 14(9), e0008365-e0008365 (2020-09-09)
Insecticide resistance poses a significant threat to the control of arthropods that transmit disease agents. Nanoparticle carriers offer exciting opportunities to expand the armamentarium of insecticides available for public health and other pests. Most chemical insecticides are delivered by contact
S D Lepore et al.
The Journal of organic chemistry, 65(10), 2924-2932 (2000-05-18)
Further exploration of the scope of our solid-phase method for the synthesis of 3-aminobenzisoxazoles (using the Kaiser oxime resin 1) is described. The effects of base, leaving group, and solvent on the nucleophilic aromatic substitution based resin-loading reaction are discussed.
Efficient synthesis of 5-(4'-methyl [1, 1'-biphenyl]-2-yl)-1H-tetrazole.
Russell RK and Murray WV.
The Journal of Organic Chemistry, 58(18), 5023-5024 (1993)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service