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Merck
CN

198803

Ethyl pipecolinate

98%

Synonym(s):

2-(Ethoxycarbonyl)piperidine, DL-Pipecolic acid ethyl ester, Ethyl 2-piperidinecarboxylate, NSC 49360

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About This Item

Empirical Formula (Hill Notation):
C8H15NO2
CAS Number:
Molecular Weight:
157.21
MDL number:
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
239-990-6
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Product Name

Ethyl pipecolinate, 98%

InChI key

SZIKRGHFZTYTIT-UHFFFAOYSA-N

InChI

1S/C8H15NO2/c1-2-11-8(10)7-5-3-4-6-9-7/h7,9H,2-6H2,1H3

SMILES string

CCOC(=O)C1CCCCN1

assay

98%

form

liquid

refractive index

n20/D 1.456 (lit.)

bp

216-217 °C (lit.)

density

1.006 g/mL at 25 °C (lit.)

functional group

ester

storage temp.

2-8°C

Application

Ethyl pipecolinate was used in the synthesis of N-substituted pipecolinates.
Reactant for:
Combinatorial chemistry with hydrazones
Swift hydroamination
Synthesis of HCV NS5B polymerase inhibitors
Preparation of selective androgen receptor modulators
Decarbonylative arylation at sp3 carbon centers
Synthesis of quinoline derivatives as selective a2C-adrenoceptor antagonists

pictograms

FlameExclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

114.8 °F - closed cup

flash_point_c

46 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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Bn MeOH 4 h 93.
Chemical Communications (Cambridge, England), 1065-1065 (1999)

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