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199222

Chromone

Name: Chromone
Brand: ALDRICH

99%

Synonym(s):

1-Benzopyran-4-one

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About This Item

Empirical Formula (Hill Notation):

C₉H₆O₂

CAS Number:

491-38-3

Molecular Weight:

146.14

NACRES:

NA.22

PubChem Substance ID:

24851900

UNSPSC Code:

12352100

EC Number:

207-737-9

MDL number:

MFCD00024064

Assay:

99%

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Properties

Quality Level

100

assay

99%

mp

55-60 °C (lit.)

functional group

ketone

SMILES string

O=C1C=COc2ccccc12

InChI

1S/C9H6O2/c10-8-5-6-11-9-4-2-1-3-7(8)9/h1-6H

InChI key

OTAFHZMPRISVEM-UHFFFAOYSA-N

Description

General description

The compounds with chromone skeleton exhibits antiradical activities that provide protection against oxidative stress.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Synthesis of Isorhamnetin-3-O-Rhamnoside by a Three-Enzyme (Rhamnosyltransferase, Glycine Max Sucrose Synthase, UDP-Rhamnose Synthase) Cascade Using a UDP-Rhamnose Regeneration System.

Anna Chen et al.

Molecules (Basel, Switzerland), 24(17) (2019-08-25)

Isorhamnetin-3-O-rhamnoside was synthesized by a highly efficient three-enzyme (rhamnosyltransferase, glycine max sucrose synthase and uridine diphosphate (UDP)-rhamnose synthase) cascade using a UDP-rhamnose regeneration system. The rhamnosyltransferase gene (78D1) from Arabidopsis thaliana was cloned, expressed, and characterized in Escherichia coli. The

Boosting Drug Discovery for Parkinson's: Enhancement of the Delivery of a Monoamine Oxidase-B Inhibitor by Brain-Targeted PEGylated Polycaprolactone-Based Nanoparticles.

Miguel Pinto et al.

Pharmaceutics, 11(7) (2019-07-25)

The current pharmacological treatments for Parkinson's disease only offer symptomatic relief to the patients and are based on the administration of levodopa and catechol-O-methyltransferase or monoamine oxidase-B inhibitors (IMAO-B). Since the majority of drug candidates fail in pre- and clinical

A chromone analog inhibits TNF-alpha induced expression of cell adhesion molecules on human endothelial cells via blocking NF-kappaB activation.

Sarvesh Kumar et al.

Bioorganic & medicinal chemistry, 15(8), 2952-2962 (2007-02-27)

The interaction between leukocytes and the vascular endothelial cells (EC) via cellular adhesion molecules plays an important role in various inflammatory and immune diseases. The molecules that block these interactions have been targeted as potential therapeutic targets for acute and

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Global Trade Item Number

SKU	GTIN
199222-5G	04061838763075