199311
Tetrabromophenol Blue
Dye content 75 %
Synonym(s):
3,3′,3″,4,5,5′,5″,6-Octabromophenolsulfonphthalein
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About This Item
Empirical Formula (Hill Notation):
C19H6Br8O5S
CAS Number:
Molecular Weight:
985.54
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
224-622-9
Beilstein/REAXYS Number:
378438
MDL number:
assay
≥75.0% (HPLC)
Quality Level
form
powder
composition
Dye content, 75%
technique(s)
microbe id | staining: suitable
mp
204 °C (dec.) (lit.)
λmax
388 nm (2nd), 605 nm
ε (extinction coefficient)
≥55000 at 606-616 nm in ethanol and water
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
Oc1c(Br)cc(cc1Br)C2(OS(=O)(=O)c3c(Br)c(Br)c(Br)c(Br)c23)c4cc(Br)c(O)c(Br)c4
InChI
1S/C19H6Br8O5S/c20-7-1-5(2-8(21)16(7)28)19(6-3-9(22)17(29)10(23)4-6)11-12(24)13(25)14(26)15(27)18(11)33(30,31)32-19/h1-4,28-29H
InChI key
QPMIVFWZGPTDPN-UHFFFAOYSA-N
Biochem/physiol Actions
Tetrabromophenol Blue (TBPB) belongs to the group of sulfonephthalein acid-base indicators. It is employed in the potentiometric titration of the halogens with Hg2(NO3)2. In addition, it has been used as a dye indicator in urine dipstick test to detect proteinuria. In this assay, with increasing concentration of urinary protein, TBPB sequentially changes color from pale green to blue. Binding of TBPB to proteins is dependent on pH.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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David S. Breslow, Herman Skolnik
Multi-Sulfur and Sulfur and Oxygen Five- and Six-Membered Heterocycles, Part 1 (2009)
Urine proteomics: the present and future of measuring urinary protein components in disease.
Barratt J and Topham P
CMAJ : Canadian Medical Association Journal = Journal de l'Association Medicale Canadienne, 177, 361-368 (2007)
Liping Li et al.
Analytica chimica acta, 1062, 102-109 (2019-04-06)
The facile detection of phosphopeptides is important for clinical screening and phosphoproteomic research. This work develops an instrument-free, cost-effective, convenient paper-based method for quantitative analysis of phosphorylated peptides. With a novel portable device, Phos-PAD, this method can achieve selective enrichment
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 199311-1G | 04061838763129 |
| 199311-5G | 04061838763136 |