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Merck
CN

199524

Chlorophenol Red

indicator grade

Synonym(s):

3′,3′-Dichlorophenolsulfonaphthalein

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About This Item

Empirical Formula (Hill Notation):
C19H12Cl2O5S
CAS Number:
4430-20-0
Molecular Weight:
423.27
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
24851922
EC Number:
224-619-2
Beilstein/REAXYS Number:
354053
MDL number:
MFCD00005877

Key Documents

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Product Name

Chlorophenol Red, indicator grade

InChI key

WWAABJGNHFGXSJ-UHFFFAOYSA-N

InChI

1S/C19H12Cl2O5S/c20-14-9-11(5-7-16(14)22)19(12-6-8-17(23)15(21)10-12)13-3-1-2-4-18(13)27(24,25)26-19/h1-10,22-23H

SMILES string

Oc1ccc(cc1Cl)C2(OS(=O)(=O)c3ccccc23)c4ccc(O)c(Cl)c4

grade

indicator grade

form

powder, crystals or chunks

color

dark brown

pH

4.8-6.7, yellow to violet

solubility

95% ethanol: 10 mg/mL

λmax

572 nm

ε (extinction coefficient)

≥12000 at 295-301 nm in 0.1 M NaOH
≥45000 at 573-579 nm in 0.1 M NaOH
≥5000 at 368-374 nm in 0.1 M NaOH

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

200

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Biochem/physiol Actions

Chlorophenol red is a pH indicator. It is used as an optical transducer of acetyl cholinesterase inhibition by the analytes. Chlorophenol red is also used to selectively determine chlorine dioxide in drinking water. It has been used in the novel assay to detect transformed protoplast-derived Zea mays colonies on Phosphinothricin (PPT).

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM9855
BCCK7535
BCCH1315
BCCJ3706
BCCH5508

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Federico Schaumburg et al.
Analytical chemistry, 91(15), 9623-9630 (2019-07-10)
Detecting bacteria is important in the fields of human health, environmental monitoring, and food safety. Foodborne pathogens alone are estimated to cause 420 000 deaths annually, with low-income regions affected most. Despite improvements in bacterial detection, fast, disposable, low-cost, sensitive, and
Lilian L L Wong et al.
The Journal of biological chemistry, 293(41), 15777-15789 (2018-08-23)
The relaxin-3 neuropeptide activates the relaxin family peptide 3 (RXFP3) receptor to modulate stress, appetite, and cognition. RXFP3 shows promise as a target for treating neurological disorders, but realization of its clinical potential requires development of smaller RXFP3-specific drugs that
Erin M O'Donoghue et al.
Plant physiology and biochemistry : PPB, 113, 208-221 (2017-03-04)
Galactose (Gal) is incorporated into cell wall polysaccharides as flowers open, but then is lost because of β-galactosidase activity as flowers mature and wilt. The significance of this for flower physiology resides in the role of galactan-containing polysaccharides in the
Selection of transformed protoplast-derived Zea mays colonies with phosphinothricin and a novel assay using the pH indicator chlorophenol red
Kramer C
Planta, 190, 454-458 (1993)
Julaluk Noiphung et al.
Theranostics, 8(14), 3797-3807 (2018-08-08)
Rationale: Saliva as a sample matrix is rapidly gaining interest for disease diagnosis and point-of-care assays because it is easy to collect (non-invasive) and contains many health-related biomarkers. However, saliva poses particular problems relative to more common urine and blood
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