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Merck
CN

199656

Sudan II

Dye content 90 %

Synonym(s):

1-(2,4-Xylylazo)-2-naphthol, Solvent Orange 7

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About This Item

Empirical Formula (Hill Notation):
C18H16N2O
CAS Number:
Molecular Weight:
276.33
PubChem Substance ID:
UNSPSC Code:
12171500
Colour Index Number:
12140
NACRES:
NA.47
EC Number:
221-490-4
MDL number:
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Product Name

Sudan II, Dye content 90 %

InChI key

JBTHDAVBDKKSRW-FMQUCBEESA-N

InChI

1S/C18H16N2O/c1-12-7-9-16(13(2)11-12)19-20-18-15-6-4-3-5-14(15)8-10-17(18)21/h3-11,21H,1-2H3/b20-19+

SMILES string

Cc1ccc(\N=N\c2c(O)ccc3ccccc23)c(C)c1

form

powder

composition

Dye content, 90%

mp

156-158 °C (lit.)

solubility

chloroform: 10 mg/mL

λmax

493 nm
604 nm (2nd)

ε (extinction coefficient)

≥14000 at 491-497 nm in methanol at 0.005 g/L
≥9000 at 419-425 nm in methanol at 0.005 g/L

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

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Application

Sudan II has been used to determine its presence in commercial spices such as hot chilli food samples (LC–ESI–MS/MS).

Biochem/physiol Actions

Sudan II is a fat-soluble synthetic colorant and it belongs to the group of azo compounds. It is classified by the international agency for research on cancer (IARC) as category 3 carcinogens because it has an ability to cause certain forms of liver and bladder cancer in animals.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

448.9 °F - closed cup

flash_point_c

231.6 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Simultaneous determination of water-soluble and fat-soluble synthetic colorants in foodstuff by high-performance liquid chromatography-diode array detection-electrospray mass spectrometry.
Ma M
Journal of Chromatography A, 1103, 170-176 (2006)
Claudio Baggiani et al.
Journal of separation science, 32(19), 3292-3300 (2009-09-02)
A method for molecularly imprinted SPE of banned Sudan azo-dyes from food samples was investigated. The molecularly imprinted polymer was obtained by suspension polymerization using 1-(4-chlorophenyl)azonaphthalen-2-ol as the mimic template. The molecular recognition properties of imprinted beads were evaluated for
Jia Wang et al.
Food chemistry, 136(3-4), 1478-1483 (2012-12-01)
A semiquantitative dip strip assay was developed using nanocolloidal gold-labelled monoclonal antibody (Mab) 8A10 for the rapid detection of Sudan red I in food samples. A protein-Sudan red I conjugate was coated on a nitro cellulose membrane strip in a
Determining the adulteration of spices with Sudan I-II-II-IV dyes by UV-visible spectroscopy and multivariate classification techniques.
Di Anibal CV
Talanta, 79, 887-892 (2009)
Shuo Sun et al.
Journal of separation science, 34(14), 1730-1737 (2011-06-10)
The liquid-liquid microextraction (LLME) was developed for extracting sudan dyes from red wine and fruit juice. Room temperature ionic liquid was used as the extraction solvent. The target analytes were determined by high-performance liquid chromatography. The extraction parameters were optimized.

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